Zhang Y, Feng B, Zhang GL, Hu M, Fu Z, Zhao F, Zhang XL, Kong L, Yu JM. Value of 18F-FDG PET-CT in surveillance of postoperative colorectal cancer patients with various carcinoembryonic antigen concentrations. World J Gastroenterol 2014; 20(21): 6608-6614 [PMID: 24914384 DOI: 10.3748/wjg.v20.i21.6608]
Corresponding Author of This Article
Jin-Ming Yu, MD, Department of Radiation Oncology, Shandong Tumor Hospital and Institute (Shandong Academy of Medical Sciences), 440# Jiyan Road, Jinan 250117, Shandong Province, China. sdyujinming@126.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jun 7, 2014; 20(21): 6608-6614 Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6608
Value of 18F-FDG PET-CT in surveillance of postoperative colorectal cancer patients with various carcinoembryonic antigen concentrations
Yan Zhang, Bin Feng, Guo-Li Zhang, Man Hu, Zheng Fu, Fen Zhao, Xiao-Li Zhang, Li Kong, Jin-Ming Yu
Yan Zhang, Jin-Ming Yu, Graduate school of Tianjin Medical University, Tianjin 300070, China
Yan Zhang, Guo-Li Zhang, Man Hu, Li Kong, Jin-Ming Yu, Department of Radiation Oncology, Shandong Tumor Hospital and Institute (Shandong Academy of Medical Sciences), Jinan 250117, Shandong Province, China
Zheng Fu, Jin-Ming Yu, Department of Nuclear Medicine, Shandong Tumor Hospital and Institute (Shandong Academy of Medical Sciences), Jinan 250117, Shandong Province, China
Fen Zhao, Jin-Ming Yu, Medical College, Shandong University, Jinan 250012, Shandong Province, China
Bin Feng, Affiliated Hospital of Shandong Academy of Medical Sciences, Jinan 250031, Shandong Province, China
Xiao-Li Zhang, School of Medicine and Life Sciences, University of Jinan, Jinan 250022, Shandong Province, China
Author contributions: Zhang Y, Kong L and Yu JM designed the study; Feng B, Zhang GL, Fu Z, Zhao F and Zhang XL collected the data and performed data analysis; Zhang Y wrote the paper; Hu M revised the paper.
Correspondence to: Jin-Ming Yu, MD, Department of Radiation Oncology, Shandong Tumor Hospital and Institute (Shandong Academy of Medical Sciences), 440# Jiyan Road, Jinan 250117, Shandong Province, China. sdyujinming@126.com
Telephone: +86-531-67626782 Fax: +86-531-67623817
Received: November 5, 2013 Revised: February 20, 2014 Accepted: March 12, 2014 Published online: June 7, 2014 Processing time: 213 Days and 16.8 Hours
Core Tip
Core tip: In this paper, fluorodeoxyglucose (FDG) positron emission tomography (PET)/computerized tomography (CT) showed an excellent diagnostic performance and its sensitivity and accuracy were significantly superior to those of CT. FDG PET/CT changed the management in some metastatic patients who might obtain the chance for a second remission. The study also showed that FDG PET/CT was effective similarly in the patients with normal and abnormal carcinoembryonic antigen (CEA) levels but had a tendency to increase with the CEA level. FDG PET/CT was an advisable option for surveillance of postoperative colorectal cancer (CRC) patients with a vague diagnosis and should be recommended in surveillance of post-operative CRC patients even with normal CEA.
