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World J Gastroenterol. Apr 28, 2014; 20(16): 4618-4625
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4618
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4618
Role of pomegranate and citrus fruit juices in colon cancer prevention
Saravana Kumar Jaganathan, Eko Supriyanto, IJN-UTM Cardiovascular Engineering Centre, Faculty of Bioscience and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia
Saravana Kumar Jaganathan, Muthu Vignesh Vellayappan, Gayathiri Narasimhan, Department of Research and Development, PSNA College of Engineering and Technology, Dindigul 624 622, India
Author contributions: Jaganathan SK designed the research; Vellayappan MV, Narasimhan G and Supriyanto E participated in the research design; Jaganathan SK, Vellayappan MV and Narasimhan G collected the literature; Vellayappan MV and Narasimhan G wrote the review in consultation with Jaganathan SK; Supriyanto E participated in writing and editing of manuscript by providing suggestions; all the authors verified the final manuscript.
Correspondence to: Saravana Kumar Jaganathan, MSc, PhD, Senior Lecturer, IJN-UTM Cardiovascular Engineering Centre, Faculty of Bioscience and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia. jaganathaniitkgp@gmail.com
Telephone: +60-7-5558548 Fax: +60-7-5558553
Received: September 25, 2013
Revised: October 31, 2013
Accepted: November 13, 2013
Published online: April 28, 2014
Processing time: 215 Days and 16.2 Hours
Revised: October 31, 2013
Accepted: November 13, 2013
Published online: April 28, 2014
Processing time: 215 Days and 16.2 Hours
Core Tip
Core tip: Recent studies prove that though chemotherapeutic agents are being used for the treatment of colon cancer, they become non-effective when the cancer progresses to an invasive stage. This problem can be minimized by the regular intake of fruit juices. The unique biochemical composition of fruit juices is responsible for their chemo-preventive properties. In this review, the chemo-preventive effects of fruit juices such as pomegranate and citrus juices against colon cancer are discussed.