Original Article
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Sep 28, 2013; 19(36): 6000-6010
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6000
Gastrointestinal stromal tumors of the duodenum: Surgical management and survival results
Xiao Liang, Hong Yu, Lin-Hua Zhu, Xian-Fa Wang, Xiu-Jun Cai
Xiao Liang, Hong Yu, Lin-Hua Zhu, Xian-Fa Wang, Xiu-Jun Cai, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: Liang X, Yu H and Cai XJ performed the majority of experiments; Zhu LH provided analytical tools and revised the manuscript; Wang XF and Cai XJ collected all the human materials and provided financial support for this work; Liang X designed the study and wrote the manuscript.
Supported by Grants from Science and Technology Department of Zhejiang Province, No. 2012C13020-2
Correspondence to: Xiu-Jun Cai, PhD, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No. 3, East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. srrshlx@163.com
Telephone: +86-571-86006276 Fax: +86-571-86006276
Received: May 4, 2013
Revised: August 3, 2013
Accepted: August 16, 2013
Published online: September 28, 2013
Core Tip

Core tip: Duodenal gastrointestinal stromal tumors (DGISTs) represent a subset of small bowel gastrointestinal stromal tumors that require special consideration given their clinical manifestations, particularly difficult surgical decisions and poor prognosis. Surgeons can choose to perform limited resection or pancreaticoduodenectomy for operable DGISTs according to the tumor size, location, proximity to the duodenal papilla, and their technical feasibility, and both these two approaches lead to a similar oncological prognosis if clear surgical margins are achieved. The prognosis of a DGIST is poor, thus comprehensive treatment is necessary.