Brief Reports
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 15, 2003; 9(7): 1625-1628
Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1625
Modified technique for combined liver-small bowel transplantation in pigs
Zhen-Yu Yin, Xiao-Dong Ni, Feng Jiang, Ning Li, You-Sheng Li, Jie-Shou Li
Zhen-Yu Yin, Feng Jiang, Xiao-Dong Li, Research Institute of General Surgery, School of Medicine, Nanjing University, Nanjing, 210093, Jiangsu Province, China
Zhen-Yu Yin, Ning Li, You-Sheng Li, Jie-Shou Li, Research Institute of General Surgery, Nanjing PLA General Hospital, Nanjing, 210002, Jiangsu Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Zhen-Yu Yin, Research Institute of General Surgery, Nanjing PLA General Hospital, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China. davidmd@sohu.com
Telephone: +8625-3685194 Fax: +86-25-4803956
Received: December 30, 2002
Revised: January 14, 2003
Accepted: February 8, 2003
Published online: July 15, 2003
Abstract

AIM: As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs.

METHODS: Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis.

RESULTS: Without immunosuppressive treatment, the median survival time of the animals was 6 d (2 to 12 d), and about 76.9% (20/26) of the animals survived for more than 4 d after operation.

CONCLUSION: The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.

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