Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1625
Revised: January 14, 2003
Accepted: February 8, 2003
Published online: July 15, 2003
AIM: As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs.
METHODS: Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis.
RESULTS: Without immunosuppressive treatment, the median survival time of the animals was 6 d (2 to 12 d), and about 76.9% (20/26) of the animals survived for more than 4 d after operation.
CONCLUSION: The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.