Basic Research
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 15, 2003; 9(5): 1063-1066
Published online May 15, 2003. doi: 10.3748/wjg.v9.i5.1063
Contents of chemical elements in stomach during prenatal development: different age-dependent dynamical changes and their significance
Shao-Fan Hou, Hai-Rong Li, Li-Zhen Wang, De-Zhu Li, Lin-Sheng Yang, Chong-Zheng Li
Shao-Fan Hou, Hai-Rong Li, Li-Zhen Wang, De-Zhu Li, Lin-Sheng Yang, Institute of Geographical Sciences and Natural Resources Research, CAS, Beijing 100101, China
Chong-Zheng Li, Beijing University of Chinese Medicine Pharmacy Huguosi Hospital, Beijing 100035, China
Author contributions: All authors contributed equally to the work.
Supported by the National Natural Science Foundation of China, No. 49971003
Correspondence to: Professor Shao-Fan Hou, Institute of Geographical Sciences and Natural Resources Research, CAS, Beijing 100101, China. lihr@igsnrr.ac.cn
Telephone: +86-10-64889796 Fax: +86-10-64851844
Received: October 30, 2002
Revised: December 2, 2002
Accepted: December 18, 2002
Published online: May 15, 2003
Abstract

AIM: To observe dynamic of different chemical elements in stomach tissue during fetal development.

METHODS: To determine contents of the 21 chemical elements in each stomach samples from fetus aging four to ten months. The content values were compared to those from adult tissue samples, and the values for each month group were also analyzed for dynamic changes.

RESULTS: Three representations were found regarding the relationship between contents of the elements and ages of the fetus, including the positive correlative (K), reversely correlative (Na, Ca, P, Al, Cu, Zn, Fe, Mn, Cr, Sr, Li, Cd, Ba, Se) and irrelevant groups (Mg, Co, Ni, V, Pb, Ti).

CONCLUSION: The chemical elements’ contents in stomach tissues were found to change dynamically with the stomach weights. The age-dependent representations for different chemical elements during the prenatal development may be of some significance for assessing development of fetal stomach and some chemical elements. The data may be helpful for the nutritional balance of fetus and mothers during prenatal development and even the perinatal stages.

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