Prospective study of nosocomial infection in 848 cases of liver diseases

doi:10.3748/wjg.v6.iSuppl3.63

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 15, 2000; 6(Suppl3): 63-63
Published online Sep 15, 2000. doi: 10.3748/wjg.v6.iSuppl3.63

Prospective study of nosocomial infection in 848 cases of liver diseases

Zhi-Jun Su, Yi-Fan Zhang, Mei-Yu Shi, Qing-Xin Zeng, Ma-Lei Chen

Zhi-Jun Su, Yi-Fan Zhang, Mei-Yu Shi, Qing-Xin Zeng, Ma-Lei Chen, Department of Hepatology, The First Hospital of Quanzhou, Quanzhou 362000, Fujian Province, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Zhi-Jun Su, Department of Hepatology, The First Hospital of Quanzhou, Quanzhou 362000, Fujian Province, China

Telephone: 595-2277281

Received: October 8, 1999
Revised: March 20, 2000
Accepted: July 10, 2000
Published online: September 15, 2000

Abstract

AIM: To study the nosocomial infection in the patients with liver diseases and its risk factors.

METHODS: A prospective survey of nosocomial infection in 848 patients with various liver diseases was carried out in our hospital for a 24-mo period.

RESULTS: Incidence of nosocomial infection in patients with liver diseases was 9.20%, nosocomial infection rate in severe hepatitis was significantly higher than in mild and moderate liver diseases. Infection of respiratory tract accounted for 44.33%. Infection rate in abdominal cavity, intestinal tract, gallbladder and bile ducts, oral region, and other regions was 15.46%, 12.37%, 8.25%, 7.22% and 12.37%, respectively.

CONCLUSION: The factors related to nosocomial infection were the severity of liver diseases, cellular immunological condition, Co-infection of hepatitis virus, severe accompanying diseases, improper medical manipulations and use of broad spectrum antibiotics. Nosocomial infection obviously affects the prognosis of liver diseases.

Keywords: Liver diseases; Cross infection; Risk factors; Prognosis