Abstracts
Copyright ©The Author(s) 2000. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 2000; 6(Suppl3): 48-48
Published online Sep 15, 2000. doi: 10.3748/wjg.v6.iSuppl3.48
Immunohistochemical study on expression of cathepsin β in gastric carcinoma
Wan-Long Lin, Cong-Jia Chen, Han-Gao Zhou
Wan-Long Lin, Cong-Jia Chen, Han-Gao Zhou, Digestive Department in Shibei Hospital, Shanghai 200435, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Wan-Long Lin, Digestive Department in Shibei Hospital, Shanghai 200435, China. Lin740129@etang.com
Telephone: +86-21-56995662
Received: November 15, 1999
Revised: March 24, 2000
Accepted: May 1, 2000
Published online: September 15, 2000
Abstract

AIM: To study the expression of cathepsin B in gastric carcinoma and its relationship with pathologic type.

METHODS: The cathepsin B expression in 54 specimens of human gastric adenocarcinoma was studied by immunohistochemistry.

RESULTS: The cathepsin B expression was detected in 33/54 (61.1%) specimens of human gastric carcinoma and in 3/54 (5.6%) of normal tissue (P < 0.01). There was no obvious correlation between the expression of cathepsin B and pathologic type of gastric adenocarcinoma.

CONCLUSION: There is a high expression of cathepsin B in human gastric adenocarcinoma.

Keywords: Stomach neoplasms; Cathepsin B; Immunohistochemistry; Adenocarcinoma