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©The Author(s) 2000. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 2000; 6(Suppl3): 35-35
Published online Sep 15, 2000. doi: 10.3748/wjg.v6.iSuppl3.35
Published online Sep 15, 2000. doi: 10.3748/wjg.v6.iSuppl3.35
Effect of Welcome on experimental gastric precancerous lessions in rats
Zhi-Yun Chen, Mao-Xiang Yan, Bai-Kang Xiang, The Digestive Diseases Research Unit of Zhejiang T.C.M. Hospital, Hangzhou 310006, Zhejiang Province, China
Author contributions: All authors contributed equally to the work.
Supported by the Natural Science Foundation of the Scientific and Technological Commission of Zhejiang Province, No. 943017
Correspondence to: Dr. Zhi-Yun Chen, Zhejiang T.C.M. Hospital, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China
Received: May 25, 2000
Revised: June 28, 2000
Accepted: July 10, 2000
Published online: September 15, 2000
Revised: June 28, 2000
Accepted: July 10, 2000
Published online: September 15, 2000
Abstract
AIM: To observe the therapeutic effect of Welcome on gastric mucosal dysplasia in rats.
METHODS: Rats with gastric mucosal dysplasia induced by MMNG and heat-damage were treated with Welcome, a kind of traditional Chinese medicine compound which has the functions of replenishing qi to invigorate the spleen, and of nourishing the liver and kidney and clearing away heat and toxic materials, the control rats were treated with saline and tretinoin.
RESULTS AND CONCLUSION: The results showed Welcome could obviously block the mutagenic action of MNNG and prevent the occurrence of gastric mucosal dysplasia of rats. the Natural Science Foundation of the Scientific and Technological Commission of Zhejiang Province, No. 943017
Keywords: Neoplasms/TCD therapy, Gastric mucosa/pathology, Precancerous conditions, Welcome, Carcinogens, Rats, Animal, laboratory