Shang D, Guan FL, Jin PY, Chen HL, Cui JH. Effect of combined therapy of Yinchenhao Chengqi decoction and endoscopic sphincterotomy for endotoxemia in acute cholangitis. World J Gastroenterol 1998; 4(5): 443-445 [PMID: 11819342 DOI: 10.3748/wjg.v4.i5.443]
Corresponding Author of This Article
Dr. Dong Shang, Second Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
Article-Type of This Article
Combined Traditional And Modera Medicine
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World J Gastroenterol. Oct 15, 1998; 4(5): 443-445 Published online Oct 15, 1998. doi: 10.3748/wjg.v4.i5.443
Effect of combined therapy of Yinchenhao Chengqi decoction and endoscopic sphincterotomy for endotoxemia in acute cholangitis
Dong Shang, Feng-Lin Guan, Pei-Yu Jin, Hai-Long Chen, Jian-Hua Cui
Dong Shang, Feng-Lin Guan, Hai-Long Chen, Second Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
Pei-Yu Jin, Jian-Hua Cui, Department of Endoscopy, First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
Dong Shang, male, born on February 5, 1971 in Liaoyang City, Liaoning Province, and graduated from Dalian Medical University as a postgraduate in 1997, attending Dalian Medical University for MD, specialized in treating the biliary tract and pancreas diseases with integrated traditional Chinese and modern medicine, having 4 papers published.
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Dong Shang, Second Department of General Surgery, First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China
Received: May 21, 1998 Revised: July 16, 1998 Accepted: August 23, 1998 Published online: October 15, 1998
Abstract
AIM: To evaluate the therapeutic mechanism of Yinchenhao Chengqi ( YCHCQ ) decoction (containing mainly Herba Artemisia capillaris) combined with endoscopic sphincterotomy (EST) for endotoxemia (ETM) in acute cholangitis.
METHODS: Twenty-one cases of acute cholangitis with ETM were divided randomly into two groups: group A, 10 patients treated with YCHCQ decoction combined with EST, group B, 11 patients treated with EST. The incidence rate of ETM, plasmic ET, serum superoxide dismutase (SOD) activity, malonyldialdehyde (MDA), complement C3 and C-reactive protein (CRP) were studied respectively.
RESULTS: The ET level of group A (35.92 ng/L ± 8.30 ng/L) was significantly reduced after 7 days of treatment (P < 0.05) in contrast to that of group B (47.8 ng/L ± 11.62 ng/L), so did the level of MDA and CRP. But the SOD activity and C3 level in group A increased significantly (P < 0.05).
CONCLUSION: YCHCQ decoction combined with EST had a beneficial effect for ETM in acute cholangitis.
