Sishengtang decoction in alleviation of toxic and side effects of transarterial embolization

doi:10.3748/wjg.v4.i2.171

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Apr 15, 1998 (publication date) through Feb 15, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Combined Traditional and Modern Medicine

World J Gastroenterol. Apr 15, 1998; 4(2): 171-173
Published online Apr 15, 1998. doi: 10.3748/wjg.v4.i2.171

Sishengtang decoction in alleviation of toxic and side effects of transarterial embolization

Zhe Chen, Chang-Quan Ling, Xue-Qiang Huang, Hong-Wu Zhang

Zhe Chen, Chang-Quan Ling, Xue-Qiang Huang, Hong-Wu Zhang, Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

Zhe Chen, male, born on 1960-05-14 in Shanghai, graduated from Shanghai University of Traditional Chinese Medicine in 1983, now associate professor, majoring cancer research, having 8 papers published.

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Zhe Chen, Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

Telephone: +86·21·65347018 ext 72341 Fax: +86·21·65562275

Received: December 2, 1997
Revised: January 4, 1998
Accepted: January 25, 1998
Published online: April 15, 1998

Abstract

AIM: To observe the therapeutic effects of Sishengtang decoction in alleviating the toxic and side effects of transarterial embolization (TAE).

METHODS: Fifty-four patients with liver cancer were divided randomly into Sishengtang decoction group (34 cases) and control group (20 cases). The changes of clinical symptoms and peripheral hemogram and some cellular immune functions were observed before and two weeks after TAE.

RESULTS: Sishengtang decoction was superior to the control group in improving the digestive tract reaction. The leucocytes of peripheral blood and cellular immune functions (activities of NK cells and LAK cells) of control group decreased obviously after TAE, while that of Sishengtang decoction group decreased slightly, without obvious difference as compared with that of preoperation.

CONCLUSIONS: Sishengtang decoction might improve the clinical symptoms and increase the leucocytes of peripheral blood and the cellular immune functions of TAE patients.

Keywords: Sishengtang decoction; liver neoplasms/therapy; embolization, therapeutic; immunity, cellular; killer cell, natural; killer cell, lymphokine-activated; leucocytes