Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2017; 23(31): 5780-5786
Published online Aug 21, 2017. doi: 10.3748/wjg.v23.i31.5780
Postoperative changes of manometry after restorative proctocolectomy in Korean ulcerative colitis patients
Se Heon Oh, Yong Sik Yoon, Jong Lyul Lee, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Se Heon Oh, Yong Sik Yoon, Jong Lyul Lee, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim, Department of Surgery, Division of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, South Korea
Author contributions: Oh SH and Yoon YS designed the research and collected, and analyzed the data, and drafted the manuscript; Lee JL, Kim CW, Park IJ, Lim SB, Yu CS and Kim JC supervised the study; all authors have read and approved the final version to be published.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Asan Medical Center (IRB No. 2017-0088).
Informed consent statement: Because this was a retrospective study with minimal risk to patients, it was exempted from obtaining informed consent by the IRB.
Conflict-of-interest statement: No conflict.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yong Sik Yoon, MD, PhD, Department of Surgery, Division of Colon and Rectal Surgery, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. yoonys@amc.seoul.kr
Telephone: +82-2-30105318 Fax: +82-2-30106701
Received: April 1, 2017
Peer-review started: April 9, 2017
First decision: April 26, 2017
Revised: May 7, 2017
Accepted: July 22, 2017
Article in press: July 24, 2017
Published online: August 21, 2017
Processing time: 139 Days and 23.5 Hours
Abstract
AIM

To investigate the changes of postoperative anal sphincter function and bowel frequency in Korean patients with ulcerative colitis (UC).

METHODS

A total of 127 patients with UC who underwent restorative proctocolectomy (RPC) during 20 years were retrospectively analyzed. The parameters of anal manometry and bowel frequency were compared according to the 6-mo intervals until 24 mo postoperatively. Manometry was used to measure the maximal squeezing pressure (MSP) and maximal resting pressure (MRP).

RESULTS

MSP decreased after surgery until 6 mo (157 to 142 mmHg); thereafter, it improved and was recovered to and maintained at the preoperative value at 12 mo postoperatively (142-170 mmHg, P < 0.001). Although the decreased MRP (65 to 56 mmHg) improved after 18 mo (62 mmHg), it did not completely recover to the preoperative value. The decreased rectal capacity after surgery (90 to 82 mL) gradually increased up to 150 mL at 24 mo. Although bowel frequency showed significant gradual decreases at each interval, it was stabilized after 12 mo postoperatively (6.5 times/d).

CONCLUSION

Postoperative changes of manometry and bowel frequency after restorative proctocolectomy in Korean patients with UC were not different from those in Western patients with UC.

Keywords: Ulcerative colitis; Surgery; Treatment outcome; Manometry; Bowel frequency; Restorative proctocolectomy

Core tip: Although there has been an increase in the prevalence of ulcerative colitis (UC) and the numbers of UC surgery in Asian countries, studies on the functional outcomes of restorative proctocolectomy (RPC) or the quality of life in Asians are still deficient. Most UC studies on functional outcomes were done in Westerners. The authors found that maximal squeezing pressure, rectal capacity, and bowel frequency were stabilized at 12 mo after RPC. Although the decreased MRP was improved after 18 mo, it did not completely recover to the preoperative value. These findings in Korean patients with UC were not different from those in Western patients with UC.