Ma C, Hao SL, Liu XC, Nin JY, Wu GC, Jiang LX, Fancellu A, Porcu A, Zheng HT. Supraclavicular lymph node metastases from malignant gastrointestinal stromal tumor of the jejunum: A case report with review of the literature. World J Gastroenterol 2017; 23(10): 1920-1924 [PMID: 28348499 DOI: 10.3748/wjg.v23.i10.1920]
Corresponding Author of This Article
Hai-Tao Zheng, PhD, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, No. 20 Yuhuangdingdong Road, Zhifu District, Yantai 264000, Shandong Province, China. machi_sdu@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 14, 2017; 23(10): 1920-1924 Published online Mar 14, 2017. doi: 10.3748/wjg.v23.i10.1920
Supraclavicular lymph node metastases from malignant gastrointestinal stromal tumor of the jejunum: A case report with review of the literature
Chi Ma, Shao-Long Hao, Xin-Cheng Liu, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Alessandro Fancellu, Alberto Porcu, Hai-Tao Zheng
Chi Ma, Jin-Yao Nin, Guo-Chang Wu, Li-Xin Jiang, Hai-Tao Zheng, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, Yantai 264000, Shandong Province, China
Shao-Long Hao, Xin-Cheng Liu, Qingdao University Medical College, Qingdao 266021, Shandong Province, China
Alessandro Fancellu, Alberto Porcu, Unit of General Surgery, Department of Clinical and Experimental Medicine, University of Sassari, 07100 Sassari, Italy
Author contributions: Ma C drafted the manuscript, and contributed to acquisition of material; Hao SL and Liu XC collected material; Ning JY collected patient’s information; Wu GC revised the manuscript, collected patient’s information; Jiang LX revised the manuscript; Fancellu A and Porcu A revised the manuscript and modified the language; Zheng HT drafted the manuscript, and contributed to the acquisition of patient’s information.
Institutional review board statement: Approved by the Yuhuangding Hospital Affiliated to Qingdao University Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There is no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hai-Tao Zheng, PhD, Department of Gastrointestinal and Thyroid Surgery, Yuhuangding Hospital Affiliated to Qingdao University, No. 20 Yuhuangdingdong Road, Zhifu District, Yantai 264000, Shandong Province, China. machi_sdu@163.com
Telephone: +86- 535-6691999 Fax: +86- 535-6691999
Received: October 26, 2016 Peer-review started: October 28, 2016 First decision: December 19, 2017 Revised: January 5, 2017 Accepted: January 18, 2017 Article in press: January 18, 2017 Published online: March 14, 2017 Processing time: 137 Days and 22.2 Hours
Abstract
Gastrointestinal stromal tumors (GISTs) represent the most common mesenchymal tumors of the alimentary tract. These tumors may have different clinical and biological behaviors. Malignant forms usually spread via a hematogenous route, and lymph node metastases rarely occur. Herein, we report a patient with a jejunal GIST who developed supraclavicular lymph node metastasis. We conclude that lymphatic diffusion via the mediastinal lymphatic station to the supraclavicular lymph nodes can be a potential metastatic route for GISTs.
Core tip: Unlike gastrointestinal carcinomas, lymph node metastases rarely develop in patients with malignant gastrointestinal stromal tumors (GISTs). We report a patient with a jejunal GIST who developed supraclavicular lymph nodes metastasis and review the related literature. We conclude that lymphatic diffusion via mediastinal lymphatic station to the supraclavicular lymph nodes can be a potential metastatic route of GISTs.
