Observational Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2016; 22(24): 5609-5615
Published online Jun 28, 2016. doi: 10.3748/wjg.v22.i24.5609
Clinical study of anesthetization by dezocine combined with propofol for indolent colonoscopy
Bin-Bin Xu, Xiao-Liang Zhao, Gui-Ping Xu
Bin-Bin Xu, Xiao-Liang Zhao, Gui-Ping Xu, Department of Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China
Author contributions: Xu BB designed the study; Zhao XL performed the study; Xu BB and Zhao XL contributed the analytical tools and analyzed the data; Xu BB and Xu GP wrote the paper.
Institutional review board statement: The study was reviewed and approved by the People’s Hospital of Xinjiang Uygur Autonomous Region Review Board.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: Technical appendix, statistical code and dataset available from the corresponding author at 56089778@qq.com. Participants have given informed consent for data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Gui-Ping Xu, Department of Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, No. 91 Tianchi Road, Urumqi 830001, Xinjiang Uygur Autonomous Region, China. xgpsyl@126.com
Telephone: +86- 991-8562209 Fax: +86-991-8562209
Received: March 13, 2016
Peer-review started: March 13, 2016
First decision: March 31, 2016
Revised: April 12, 2016
Accepted: May 21, 2016
Article in press: May 23, 2016
Published online: June 28, 2016
Processing time: 100 Days and 6 Hours
Abstract

AIM: To assess the use of dezocine combined with propofol for the anesthetization of patients undergoing indolent colonoscopy.

METHODS: A cross-sectional survey of patients undergoing indolent colonoscopy in the Xinjiang People’s Hospital was conducted from April 1 to April 30, 2015. The survey collected patient general information and anesthesia data, including overall medical experience and pain management. Thirty minutes after colonoscopy surgery, samples of venous blood were collected and the biochemical indicators of gastrointestinal function were analyzed.

RESULTS: There were 98 female and 62 male respondents. Indolent colonoscopy was found to be more suitable for mid to older-aged patients. The necessary conditions for the diagnosis of digestive diseases were required in 65 of the 73 inpatients. Adverse reactions to the intraoperative process included two cases of body movement and two cases of respiratory depression. Gastrin and vasoactive intestinal peptide levels were slightly increased. However, somatostatin and endothelin levels were slightly decreased.

CONCLUSION: This study revealed that dezocine combined with propofol can be successfully used for the anesthetization of indolent colonoscopy patients without pain and should be widely used.

Keywords: Dezocine; Propofol; Colonoscopy; Patient assessment; Anesthetization; Cross-sectional

Core tip: A cross-sectional survey of patients undergoing indolent colonoscopy was carried out to study the clinical effect of anesthetization by dezocine combined with propofol. Thirty minutes after colonoscopy surgery, samples of venous blood were collected and the biochemical indicators of gastrointestinal function were analyzed. Indolent colonoscopy was found to be more suitable for mid to older-aged patients. Gastrin and vasoactive intestinal peptide levels were slightly increased. However, somatostatin and endothelin levels were slightly decreased. This study revealed that dezocine combined with propofol can be successfully used for the anesthetization of indolent colonoscopy patients without pain and should be widely used.