Systematic Reviews
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2015; 21(28): 8670-8677
Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8670
Current state of laparoscopic parastomal hernia repair: A meta-analysis
Francis J DeAsis, Brittany Lapin, Matthew E Gitelis, Michael B Ujiki
Francis J DeAsis, Brittany Lapin, Matthew E Gitelis, Michael B Ujiki, Section of Minimally Invasive Surgery, Department of Surgery, NorthShore University Health System, Evanston, IL 60201, United States
Author contributions: DeAsis FJ, Lapin B, Gitelis ME and Ujiki MB contributed solely to this paper.
Conflict-of-interest statement: Michael B Ujiki is a consultant for Covidien and a speaker for Gore. Francis J DeAsis, Brittany Lapin, and Matthew E Gitelis report no potential conflicts of interest.
Data sharing statement: Dataset available from the corresponding author at mujiki@northshore.org.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Michael B Ujiki, MD, FACS, Section of Minimally Invasive Surgery, Department of Surgery, NorthShore University Health System, 2650 Ridge Avenue Evanston, IL 60201, United States. mujiki@northshore.org
Telephone: +1-847-5701700 Fax: +1-847-5701330
Received: January 14, 2015
Peer-review started: January 14, 2015
First decision: March 26, 2015
Revised: April 8, 2015
Accepted: May 20, 2015
Article in press: May 21, 2015
Published online: July 28, 2015
Processing time: 197 Days and 7 Hours
Abstract

AIM: To evaluate the efficacy and safety of the laparoscopic approaches for parastomal hernia repair reported in the literature.

METHODS: A systematic review of PubMed and MEDLINE databases was conducted using various combination of the following keywords: stoma repair, laparoscopic, parastomal, and hernia. Case reports, studies with less than 5 patients, and articles not written in English were excluded. Eligible studies were further scrutinized with the 2011 levels of evidence from the Oxford Centre for Evidence-Based Medicine. Two authors reviewed and analyzed each study. If there was any discrepancy between scores, the study in question was referred to another author. A meta -analysis was performed using both random and fixed-effect models. Publication bias was evaluated using Begg’s funnel plot and Egger’s regression test. The primary outcome analyzed was recurrence of parastomal hernia. Secondary outcomes were mesh infection, surgical site infection, obstruction requiring reoperation, death, and other complications. Studies were grouped by operative technique where indicated. Except for recurrence, most postoperative morbidities were reported for the overall cohort and not by approach so they were analyzed across approach.

RESULTS: Fifteen articles with a total of 469 patients were deemed eligible for review. Most postoperative morbidities were reported for the overall cohort, and not by approach. The overall postoperative morbidity rate was 1.8% (95%CI: 0.8-3.2), and there was no difference between techniques. The most common postoperative complication was surgical site infection, which was seen in 3.8% (95%CI: 2.3-5.7). Infected mesh was observed in 1.7% (95%CI: 0.7-3.1), and obstruction requiring reoperation also occurred in 1.7% (95%CI: 0.7-3.0). Other complications such as ileus, pneumonia, or urinary tract infection were noted in 16.6% (95%CI: 11.9-22.1). Eighty-one recurrences were reported overall for a recurrence rate of 17.4% (95%CI: 9.5-26.9). The recurrence rate was 10.2% (95%CI: 3.9-19.0) for the modified laparoscopic Sugarbaker approach, whereas the recurrence rate was 27.9% (95%CI: 12.3-46.9) for the keyhole approach. There were no intraoperative mortalities reported and six mortalities during the postoperative course.

CONCLUSION: Laparoscopic intraperitoneal mesh repair is safe and effective for treating parastomal hernia. A modified Sugarbaker approach appears to provide the best outcomes.

Keywords: Parastomal; Hernia; Laparoscopic; Repair; Treatment; Sugarbaker; Keyhole; Sandwich; Ileostomy; Colostomy

Core tip: Parastomal hernia is a common morbidity following stoma creation. Outcomes following repair of such hernias are relatively poor. Given the success of laparoscopy in repairing ventral hernia, we present the current laparoscopic options for repairing the defect.