Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5744
Peer-review started: November 19, 2014
First decision: December 26, 2014
Revised: January 19, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 14, 2015
Processing time: 180 Days and 22.1 Hours
Situs inversus viscerum (SIV) is a rare congenital condition characterized by complete transposition of all viscera. This anatomical pathology makes endoscopic retrograde cholangiopancreatography (ERCP) technically difficult. We report a new case of a 70-year-old Chinese male with total SIV who had obstructive jaundice. Magnetic resonance cholangiopancreatography demonstrated a number of stones in the gallbladder and common bile duct (CBD). Therapeutic ERCP was performed to relieve biliary obstruction and remove the CBD stones. This procedure started with the patient in a supine position and the endoscopist at the left side of the table. When the papilla was maintained, the patient was repositioned to a prone position and standard endoscopic sphincterotomy and endoscopic papillary balloon dilatation procedures were conducted. ERCP was performed successfully and relevant complications did not occur in this patient. We also present a review of the literature published between 1985 and 2014 in the PubMed and EMBASE databases. There were eight published cases during this period, with one each from America, Finland, India, Italy, South Korea and Pakistan, and two from Spain. Our case is the first reported in China.
Core tip: Endoscopic retrograde cholangiopancreatography (ERCP) is widely applied for the diagnosis and treatment of pancreaticobiliary disease. However, this approach can be challenging in cases of anatomical variations. Total situs inversus viscerum (SIV) is a rare condition that involves a 180° reversal of all the visceral positions, which increases the difficulty of ERCP. Endoscopic access to the papilla and subsequent cannulation are difficult in these patients. However, we successfully overcame these difficulties by changing the patient’s positions during the procedure. Standard endoscopic sphincterotomy and endoscopic papillary balloon dilatation procedures were performed with no complications. Herein, we also review several related cases with summary information, key steps and technique information for ERCP in patients with SIV.