Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3759-3762
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3759
Gastritis cystica profunda in a previously unoperated stomach: A case report
Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng
Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng, Department of Surgical Oncology, The 1st Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Teng LS designed the report; Chen ST collected the patient’s clinical data; Guo LW and Yu XF analyzed the data and wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li-Song Teng, PhD, Director, Department of Surgical Oncology, The 1st Affiliated Hospital, School of Medicine, Zhejiang University, 79, Qingchun Road, Hangzhou 310003, Zhejiang Province, China. lsteng@zju.edu.cn
Telephone: +86-571-87236878 Fax: +86-571-87236878
Received: August 1, 2014
Peer-review started: August 3, 2014
First decision: August 27, 2014
Revised: September 11, 2014
Accepted: November 18, 2014
Article in press: November 19, 2014
Published online: March 28, 2015
Processing time: 241 Days and 13.7 Hours
Abstract

Gastritis cystica profunda is a relatively rare disease, usually observed at anastomotic sites in stomachs of patients that have undergone gastric procedures. We present the rare case of an elevated lesion in the anterior wall of the gastric antrum of a 43-year-old Chinese woman who had never undergone gastric surgery and had no gastrointestinal tract symptoms. Although the physical examination and laboratory data showed no abnormalities, endoscopic ultrasonography revealed an anechoic cystic structure. Abdominal computed tomography and magnetic resonance imaging showed the gastric wall of the greater curvature of the antrum was markedly and irregularly thickened, and mild to moderate enhancement was observed around the lesion with no enhancement in the central portion, suggestive of a gastrointestinal stromal tumor. The patient underwent a distal gastric resection of the 2.5 cm × 1.5 cm lesion. A postoperative pathologic examination showed dilated cystic glands in the muscularis mucosa and submucosal layers and erosion of the mucosal surface of the tumor, confirming the diagnosis of gastritis cystica profunda without malignancy.

Keywords: Gastritis cystica profunda; Hyperplastic polyp; Stomach

Core tip: Gastritis cystica profunda is a rare disease characterized by polypoid hyperplasia and cystic dilatation of the gastric glands extending into the submucosa of the stomach. It is typically only found in the stomach after gastric surgery, however, we encountered a rare case of gastritis cystica profunda in a 43-year-old Chinese woman who had never undergone gastric surgery. The elevated lesion in the anterior wall of the gastric antrum was discovered by endoscopic ultrasonography, and marked and irregular thickening of the gastric wall was observed with computed tomography and magnetic resonance imaging.