Abstracts
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 215-215
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.215
Initiative investigation on the level of plasma motilin in diarrhea and constipation
Qing-Ming Wu, Ming-Zi Mao, Zhen Rong, Kai-Sen Yu
Qing-Ming Wu, Ming-Zi Mao, Zhen Rong, Kai-Sen Yu, Affiliated Hospital of Yunyang Medical School, Shiyan 442000, Hubei Province, China
Author contributions: All authors contributed equally to the work.
Received: December 11, 1995
Revised: January 21, 1996
Accepted: May 19, 1996
Published online: September 15, 1996
Abstract

AIM: Motilin is a brain gut peptide that revealed a more widespread distribution of the GI tract and central nervous system. Motilin is considered a major determinant of phase 3 activity of the migrating motor complex (MMC) in the stomach and upper small bowel, causing contraction of gastric and intestinal smooth muscle. In this paper, the effect of motilin on the colonic motility was studied.

METHODS: The levels of fast plasma motilin were detected for the reversal motility disorders types diarrhea and constipations, 50 cases respectively, and 30 health controls.

RESULTS: The concentrations of motilin in the diseases group was significantly increased in the group of diarrhea than in the group of constipation.

CONCLUSION: Motilin may play a role in the motility of colon.

Keywords: Motilin; Colon transit