Abstracts
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 189-189
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.189
Clinical observation of cisapride in the treatment of 54 cases of gastroptosis
Jian-Zhen Wen, Shu-Ying Wang, Ai-Fang Wu
Jian-Zhen Wen, Shu-Ying Wang, Ai-Fang Wu, Jiang Shuzhen Laiyang Ceneral Hospital, Shandong Province, China
Author contributions: All authors contributed equally to the work.
Received: December 11, 1995
Revised: January 21, 1996
Accepted: July 19, 1996
Published online: September 15, 1996
Abstract

AIM: Cisapride is a new gastro prokinetic agonist which can stimulate the 5HT4 receptor of the motive neuron in the muscular neuroplexus. It can stimulate the release of acetylcholine, strengthen the peristaltic contraction of the esophagus and stomach and increase the speed of emptying the stomach. We began to use cisapride with WEI-SU pulvis in 1994 in our hospital. Since then we have treated 54 cases of gastroptosis. The total effective rate was 100% (P < 0.01). It does not pass through the blood brain barrier and it is safe. The clinical practice showed that cisapride with WEI-SU pulvis is effective in the treatment of gastroptosis. The medicine is worth spreading and using in the clinic.

Keywords: Cisapride, WEI-SU pulvis, Gastroptosis