Published online Oct 28, 2013. doi: 10.3748/wjg.v19.i40.6842
Revised: August 1, 2013
Accepted: September 13, 2013
Published online: October 28, 2013
Processing time: 188 Days and 15.7 Hours
AIM: To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.
METHODS: We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography (CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis (PEA) or left acute colonic diverticulitis (ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics, laboratory findings, treatments, and clinical results of left PEA with those of left ACD.
RESULTS: Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD, respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant (82.1%). On CT examination, most (89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD, the patients presented with a more diffuse abdominal tenderness throughout the left side (52.0% vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA (40.0% vs 7.1%, P = 0.004; 52.0% vs 14.3%, P = 0.003, respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD (52.0% vs 15.4%, P = 0.006).
CONCLUSION: If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities, clinicians should suspect the diagnosis of PEA and consider a CT scan.
Core tip: The clinical symptoms of primary epiploic appendagitis (PEA) and acute colonic diverticulitis (ACD) are similar in patients presenting with left-sided abdominal pain. In our study, the patients with PEA had well-localized abdominal tenderness, whereas those with ACD presented with slightly diffuse abdominal tenderness. The patients with ACD showed fever, rebound tenderness, and leukocytosis more often than those with PEA. When patients have well-localized abdominal tenderness without associated systemic manifestation or laboratory abnormalities, clinicians should suspect a diagnosis of PEA and consider a computer tomography (CT) scan. The characteristic CT findings of PEA may enable clinicians to accurately diagnose the disease.