Brief Article
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Feb 21, 2012; 18(7): 666-672
Published online Feb 21, 2012. doi: 10.3748/wjg.v18.i7.666
Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding
Takayoshi Shishido, Shiro Oka, Shinji Tanaka, Hiroki Imagawa, Yoshito Takemura, Shigeto Yoshida, Kazuaki Chayama
Takayoshi Shishido, Hiroki Imagawa, Yoshito Takemura, Kazuaki Chayama, Department of Gastroenterology, Hiroshima University, Hiroshima 734-8551, Japan
Shiro Oka, Shinji Tanaka, Shigeto Yoshida, Department of Endoscopy, Hiroshima University Hospital, Hiroshima 734-8551, Japan
Author contributions: Shishido T and Oka S designed the study and wrote the article; Tanaka S, Imagawa H, Takemura Y, Yoshida S and Chayama K performed the research.
Correspondence to: Shiro Oka, MD, PhD, Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. oka4683@hiroshima-u.ac.jp
Telephone: +81-82-2575538 Fax: +81-82-2575538
Received: January 16, 2011
Revised: April 20, 2011
Accepted: April 27, 2011
Published online: February 21, 2012
Abstract

AIM: To assess the diagnostic success and outcome among patients with obscure gastrointestinal bleeding who underwent total enteroscopy with double-balloon endoscopy.

METHODS: Total enteroscopy was attempted in 156 patients between August 2003 and June 2008 at Hiroshima University Hospital and achieved in 75 (48.1%). It is assessed whether sources of bleeding were identified, treatment methods, complications, and 1-year outcomes (including re-bleeding) after treatment, and we compared re-bleeding rates among patients.

RESULTS: The source of small bowel bleeding was identified in 36 (48.0%) of the 75 total enteroscopy patients; the source was outside the small bowel in 11 patients (14.7%) and not identified in 28 patients (37.3%). Sixty-one of the 75 patients were followed up for more than 1 year (27.2 ± 13.3 mo). Four (6.6%) of these patients showed signs of re-bleeding during the first year, but bleeding did not recur after treatment. Although statistical significance was not reached, a marked difference was found in the re-bleeding rate between patients in whom total enteroscopy findings were positive (8.6%, 3/35) and negative (3.8%, 1/26) (3/35 vs 1/26, P = 0.63).

CONCLUSION: A good outcome can be expected for patients who undergo total enteroscopy and receive proper treatment for the source of bleeding in the small bowel.

Keywords: Double-balloon endoscopy, Small bowel, Obscure gastrointestinal bleeding, Total enteroscopy, Outcome