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World J Gastroenterol. Feb 14, 2012; 18(6): 587-588
Published online Feb 14, 2012. doi: 10.3748/wjg.v18.i6.587
Published online Feb 14, 2012. doi: 10.3748/wjg.v18.i6.587
Gastrointestinal stromal tumor and mitosis, pay attention
Federico Coccolini, Luca Ansaloni, General and Emergency Surgery Department Ospedali Riuniti, 24128 Bergamo, Italy
Fausto Catena, Antonio Daniele Pinna, General and Transplant Surgery Department, Sant’Orsola-Malpighi University Hospital, 24128 Bologna, Italy
Author contributions: Coccolini F and Catena F contributed equally to this work by writing the letter; Ansaloni L and Pinna AD gave the final approval.
Correspondence to: Federico Coccolini, MD, General and Emergency Surgery Department, Ospedali Riuniti, Largo Barozzi 1, 24128 Bergamo, Italy. fedecocco@iol.it
Telephone: +39-0352-66464 Fax: +39-0352-66567
Received: June 8, 2011
Revised: September 9, 2011
Accepted: October 14, 2011
Published online: February 14, 2012
Revised: September 9, 2011
Accepted: October 14, 2011
Published online: February 14, 2012
Abstract
The difference between stages I and III of gastric gastrointestinal stromal tumor depends principally on the number of mitosis. According with TNM classification, the presence in the tumor of high mitotic rate determines the upgrading. Many studies exposed different count techniques in evaluating the number of mitosis. An international standardized method to assess mitotic rate is needed.