Brief Article
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World J Gastroenterol. Jul 28, 2012; 18(28): 3705-3709
Published online Jul 28, 2012. doi: 10.3748/wjg.v18.i28.3705
ERCP for the treatment of bile leak after partial hepatectomy and fenestration for symptomatic polycystic liver disease
Nayantara Coelho-Prabhu, David M Nagorney, Todd H Baron
Nayantara Coelho-Prabhu, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
David M Nagorney, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
Todd H Baron, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
Author contributions: Coelho-Prabhu N, Nagorney DM and Baron TH designed the study; Coelho-Prabhu N collected the data and analyzed the results; Coelho-Prabhu N and Baron TH wrote the manuscript; all authors approved the final version of the manuscript.
Correspondence to: Todd H Baron, MD, FASGE, Professor of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, United States. baron.todd@mayo.edu
Telephone: +1-507-2842407 Fax: +1-507-2840538
Received: June 9, 2011
Revised: December 14, 2011
Accepted: March 10, 2012
Published online: July 28, 2012
Abstract

AIM: To describe endoscopic treatment of bile leaks in these patients and to identify risk factors in these patients which can predict the development of bile leaks.

METHODS: Retrospective case-control study examining consecutive patients who underwent partial hepatectomy for polycystic liver disease (PLD) and developed a postoperative bile leak managed endoscopically over a ten year period. Each case was matched with two controls with PLD who did not develop a postoperative bile leak.

RESULTS: Ten cases underwent partial hepatectomy with fenestration for symptoms including abdominal distention, pain and nausea. Endoscopic retrograde cholangiopancreatography (ERCP) showed anatomic abnormalities in 1 case. A biliary sphincterotomy was performed in 4 cases. A plastic biliary stent was placed with the proximal end at the site of the leak in 9 cases; in 1 case two stents were placed. The overall success rate of ERCP to manage the leak was 90%. There were no significant differences in age, gender, comorbidities, duration of symptoms, history of previous surgery or type of surgery performed between cases and controls.

CONCLUSION: ERCP with stent placement is safe and effective for management of post-hepatectomy bile leak in patients with PLD.

Keywords: Polycystic liver, Hepatectomy, Bile leak, Endoscopic retrograde cholangiopancreatography