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World J Gastroenterol. May 28, 2010; 16(20): 2463-2467
Published online May 28, 2010. doi: 10.3748/wjg.v16.i20.2463
Published online May 28, 2010. doi: 10.3748/wjg.v16.i20.2463
Clinical features of hepatitis B virus-related hepatocellular carcinoma
Toru Ishikawa, Department of Gastroenterology and Hepatology, Saiseikai Niigata Second Hospital, Niigata 950-1104, Japan
Author contributions: Ishikawa T contributed all to this paper.
Correspondence to: Toru Ishikawa, MD, Department of Gastroenterology and Hepatology, Saiseikai Niigata Second Hospital, Teraji 280-7, Niigata 950-1104, Japan. toruishi@ngt.saiseikai.or.jp
Telephone: +81-25-2336161 Fax: +81-25-2338880
Received: December 28, 2009
Revised: February 10, 2010
Accepted: February 17, 2010
Published online: May 28, 2010
Revised: February 10, 2010
Accepted: February 17, 2010
Published online: May 28, 2010
Abstract
Hepatocellular carcinoma (HCC) is a major cause of cancer death, and chronic hepatitis B is a serious worldwide problem. The epidemiology of HCC is distinctive. Hepatitis B virus (HBV) plays a major role in hepatocarcinogenesis. Prevention of HBV-related HCC is a key issue in current hepatology. This paper describes the prevention and clinical features of HBV-related HCC, along with a short review of the disease.
Keywords: Hepatocellular carcinoma; Hepatitis B virus