Letters To The Editor
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Apr 21, 2008; 14(15): 2454-2455
Published online Apr 21, 2008. doi: 10.3748/wjg.14.2454
Non-invasive prediction of oesophageal varices in cirrhosis
Sambit Sen, William JH Griffiths
Sambit Sen, William JH Griffiths, Department of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom
Author contributions: Griffiths WJH designed and performed the research; Sen S analyzed the data; Griffiths WJH and Sen S co-wrote the paper.
Correspondence to: William JH Griffiths, Consultant Hepatologist, Department of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Addenbrookes Hospital, Cambridge CB2 0QQ, United Kingdom. bill.griffiths@addenbrookes.nhs.uk
Telephone: +44-1223-586891
Fax: +44-1223-216111
Received: December 13, 2007
Revised: January 21, 2008
Published online: April 21, 2008
Abstract

Non-invasive predictors of varices in cirrhosis would reduce the need for screening endoscopies. Platelet count and spleen size have been shown to be useful parameters, in mixed groups of cirrhotics with different aetiologies. We evaluated this in two homogeneous groups with cirrhosis due to hepatitis C and alcohol. Non-invasive predictors appear promising in the former group, but less so in the latter group.

Keywords: Varices, Cirrhosis, Endoscopy, Platelet, Spleen