For: | Huda N, Liu G, Hong H, Yan S, Khambu B, Yin XM. Hepatic senescence, the good and the bad. World J Gastroenterol 2019; 25(34): 5069-5081 [PMID: 31558857 DOI: 10.3748/wjg.v25.i34.5069] |
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URL: | https://www.wjgnet.com/1007-9327/full/v25/i34/5069.htm |
Number | Citing Articles |
1 |
Kai Kang, Anran Xia, Fanrui Meng, Jian Chunyu, Xu Sun, Guiping Ren, Dan Yu, Xinghao Jiang, Lei Tang, Wei Xiao, Deshan Li. FGF21 alleviates chronic inflammatory injury in the aging process through modulating polarization of macrophages. International Immunopharmacology 2021; 96: 107634 doi: 10.1016/j.intimp.2021.107634
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2 |
Dorian V. Ziegler, Nadine Martin, David Bernard. Cellular senescence links mitochondria-ER contacts and aging. Communications Biology 2021; 4(1) doi: 10.1038/s42003-021-02840-5
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3 |
Priyanka Banerjee, Sivareddy Kotla, Loka Reddy Velatooru, Rei J. Abe, Elizabeth A. Davis, John P. Cooke, Keri Schadler, Anita Deswal, Joerg Herrmann, Steven H. Lin, Jun-ichi Abe, Nhat-Tu Le. Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer. Frontiers in Cardiovascular Medicine 2021; 8 doi: 10.3389/fcvm.2021.763930
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4 |
Johanna Pedroza-Diaz, Johanna C. Arroyave-Ospina, Sandra Serna Salas, Han Moshage. Modulation of Oxidative Stress-Induced Senescence during Non-Alcoholic Fatty Liver Disease. Antioxidants 2022; 11(5): 975 doi: 10.3390/antiox11050975
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5 |
Tirthadipa Pradhan-Sundd, Gregory J. Kato, Enrico M. Novelli. Molecular mechanisms of hepatic dysfunction in sickle cell disease: lessons from Townes mouse model. American Journal of Physiology-Cell Physiology 2022; 323(2): C494 doi: 10.1152/ajpcell.00175.2022
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6 |
Yihua Huang, Xue Yang, Yan Meng, Changchun Shao, Jianping Liao, Fengwei Li, Rong Li, Yingying Jing, Aimin Huang. The hepatic senescence-associated secretory phenotype promotes hepatocarcinogenesis through Bcl3-dependent activation of macrophages. Cell & Bioscience 2021; 11(1) doi: 10.1186/s13578-021-00683-5
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7 |
Joy X. Jiang, Sarah R. Fish, Alexey Tomilov, Yuan Li, Weiguo Fan, Ali Dehnad, David Gae, Suvarthi Das, Gergely Mozes, Gregory W. Charville, Jon Ramsey, Gino Cortopassi, Natalie J. Török. Nonphagocytic Activation of NOX2 Is Implicated in Progressive Nonalcoholic Steatohepatitis During Aging. Hepatology 2020; 72(4): 1204 doi: 10.1002/hep.31118
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8 |
Mark Li, Ling Yang. Autophagy in Health and Disease. 2022; : 161 doi: 10.1016/B978-0-12-822003-0.00014-0
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9 |
Yujing Zhang, Gang Yang, Shuai Huang, Xinyue Yang, Fengyan Yuan, Yinghui Song, Sulai Liu, Xing Yu, Josep Rubert. Regulation of Cr(VI)-Induced Premature Senescence in L02 Hepatocytes by ROS-Ca2+-NF-κB Signaling. Oxidative Medicine and Cellular Longevity 2022; 2022: 1 doi: 10.1155/2022/7295224
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10 |
Subramanian Muthamil, Hyun‐Yong Kim, Hyun‐Jun Jang, Ji‐Hyo Lyu, Ung Cheol Shin, Younghoon Go, Seong‐Hoon Park, Hee Gu Lee, Jun Hong Park. Biomarkers of Cellular Senescence and Aging: Current State‐of‐the‐Art, Challenges and Future Perspectives. Advanced Biology 2024; 8(9) doi: 10.1002/adbi.202400079
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11 |
Julia Kallenbach, Golnaz Atri Roozbahani, Mehdi Heidari Horestani, Aria Baniahmad. Distinct mechanisms mediating therapy-induced cellular senescence in prostate cancer. Cell & Bioscience 2022; 12(1) doi: 10.1186/s13578-022-00941-0
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12 |
Kensuke Kitsugi, Hidenao Noritake, Moe Matsumoto, Tomohiko Hanaoka, Masahiro Umemura, Maho Yamashita, Shingo Takatori, Jun Ito, Kazuyoshi Ohta, Takeshi Chida, Barbara Ulmasov, Brent A. Neuschwander-Tetri, Takafumi Suda, Kazuhito Kawata. Arg-Gly-Asp-binding integrins activate hepatic stellate cells via the hippo signaling pathway. Cellular Signalling 2022; 99: 110437 doi: 10.1016/j.cellsig.2022.110437
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13 |
Małgorzata Łysek-Gładysińska, Anna Wieczorek, Artur Jóźwik, Anna Walaszczyk, Karol Jelonek, Grażyna Szczukiewicz-Markowska, Olaf K. Horbańczuk, Monika Pietrowska, Piotr Widłak, Dorota Gabryś. Aging-Related Changes in the Ultrastructure of Hepatocytes and Cardiomyocytes of Elderly Mice Are Enhanced in ApoE-Deficient Animals. Cells 2021; 10(3): 502 doi: 10.3390/cells10030502
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14 |
Yongyuan He, Yinghong Su, Chengcheng Duan, Siyuan Wang, Wei He, Yingting Zhang, Xiaofei An, Ming He. Emerging role of aging in the progression of NAFLD to HCC. Ageing Research Reviews 2023; 84: 101833 doi: 10.1016/j.arr.2022.101833
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15 |
Chittampalli N. Yashaswini, Tianyue Qin, Dipankar Bhattacharya, Corina Amor, Scott Lowe, Amaia Lujambio, Shuang Wang, Scott L. Friedman. Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis. Journal of Hepatology 2024; 81(2): 207 doi: 10.1016/j.jhep.2024.03.014
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16 |
April O’Brien, Tianhao Zhou, Tori White, Abigail Medford, Lixian Chen, Konstantina Kyritsi, Nan Wu, Jonathan Childs, Danaleigh Stiles, Ludovica Ceci, Sanjukta Chakraborty, Burcin Ekser, Leonardo Baiocchi, Guido Carpino, Eugenio Gaudio, Chaodong Wu, Lindsey Kennedy, Heather Francis, Gianfranco Alpini, Shannon Glaser. FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis. Hepatology Communications 2022; 6(7): 1574 doi: 10.1002/hep4.1909
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17 |
Nidhi Jalan-Sakrikar, Maria Eugenia Guicciardi, Steven P. O’Hara, Adiba Azad, Nicholas F. LaRusso, Gregory J. Gores, Robert C. Huebert. Central role for cholangiocyte pathobiology in cholestatic liver diseases. Hepatology 2024; doi: 10.1097/HEP.0000000000001093
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18 |
Raquel Maeso-Díaz, Jordi Gracia-Sancho. Aging and Chronic Liver Disease. Seminars in Liver Disease 2020; 40(04): 373 doi: 10.1055/s-0040-1715446
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19 |
Avadh Kumar, Daniele Bano, Dan Ehninger. Cellular senescence in vivo: From cells to tissues to pathologies. Mechanisms of Ageing and Development 2020; 190: 111308 doi: 10.1016/j.mad.2020.111308
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20 |
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21 |
Rupa Lavarti, Lun Cai, Tatiana Alvarez‐Diaz, Thalia Medina‐Rodriguez, Sergei Bombin, Raghavan Pillai Raju. Senescence landscape in the liver following sepsis and senolytics as potential therapeutics. Aging Cell 2025; 24(1) doi: 10.1111/acel.14354
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22 |
Varvara A. Kirchner, Joshua S. Badshah, Suk Kyun Hong, Olivia Martinez, Timothy L. Pruett, Laura J. Niedernhofer. Effect of Cellular Senescence in Disease Progression and Transplantation: Immune Cells and Solid Organs. Transplantation 2023; doi: 10.1097/TP.0000000000004838
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23 |
Wei Zhu, Xiaofen Zhang, Mengli Yu, Bingru Lin, Chaohui Yu. Radiation-induced liver injury and hepatocyte senescence. Cell Death Discovery 2021; 7(1) doi: 10.1038/s41420-021-00634-6
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24 |
Stefania Moscato, Manuela Cabiati, Francesco Bianchi, Daniele Panetta, Silvia Burchielli, Gabriele Massimetti, Silvia Del Ry, Letizia Mattii. Heart and liver connexin expression related to the first stage of aging: A study on naturally aged animals. Acta Histochemica 2020; 122(8): 151651 doi: 10.1016/j.acthis.2020.151651
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25 |
Rosa Spinelli, Ritesh Kumar Baboota, Silvia Gogg, Francesco Beguinot, Matthias Blüher, Annika Nerstedt, Ulf Smith. Increased cell senescence in human metabolic disorders. Journal of Clinical Investigation 2023; 133(12) doi: 10.1172/JCI169922
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26 |
Tianhao Zhou, Debjyoti Kundu, Jonathan Robles-Linares, Vik Meadows, Keisaku Sato, Leonardo Baiocchi, Burcin Ekser, Shannon Glaser, Gianfranco Alpini, Heather Francis, Lindsey Kennedy. Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease. Cells 2021; 10(8): 2072 doi: 10.3390/cells10082072
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27 |
Jie He, Xiaoyan Li. Identification and Validation of Aging-Related Genes in Idiopathic Pulmonary Fibrosis. Frontiers in Genetics 2022; 13 doi: 10.3389/fgene.2022.780010
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28 |
Nouf Aljobaily, Michael J. Viereckl, David S. Hydock, Hend Aljobaily, Tsung-Yen Wu, Raquel Busekrus, Brandon Jones, Jammie Alberson, Yuyan Han. Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence. Nutrients 2020; 13(1): 41 doi: 10.3390/nu13010041
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29 |
Consuelo Lomas‐Soria, Laura A. Cox, Peter W. Nathanielsz, Elena Zambrano. Sexual dimorphism in liver cell cycle and senescence signalling pathways in young and old rats. The Journal of Physiology 2021; 599(18): 4309 doi: 10.1113/JP281822
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30 |
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31 |
Haoyu Xue, Huizhong Nie, Zhenlin Huang, Bin Lu, Mengjuan Wei, Hong Xu, Lili Ji. 2,3,5,4′-tetrahydroxy-stilbene-2-O-β-D-glucoside promotes liver regeneration after partial hepatectomy in mice: The potential involvement of PPARα-mediated fatty acid metabolism. Journal of Ethnopharmacology 2024; 334: 118513 doi: 10.1016/j.jep.2024.118513
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32 |
Miaomiao Wei, Xinlong Yan, Xin Xin, Haiqiang Chen, Lingling Hou, Jinhua Zhang. Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway. International Journal of Molecular Sciences 2022; 23(19): 11696 doi: 10.3390/ijms231911696
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33 |
Alexis Hernández-Magaña, Antonio Bensussen, Juan Carlos Martínez-García, Elena R. Álvarez-Buylla. A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence. npj Systems Biology and Applications 2024; 10(1) doi: 10.1038/s41540-024-00422-9
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34 |
Sebastian J. Wallace, Frank Tacke, Robert F. Schwabe, Neil C. Henderson. Understanding the cellular interactome of non-alcoholic fatty liver disease. JHEP Reports 2022; 4(8): 100524 doi: 10.1016/j.jhepr.2022.100524
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35 |
Xinghui Sun, Edward N. Harris. New aspects of hepatic endothelial cells in physiology and nonalcoholic fatty liver disease. American Journal of Physiology-Cell Physiology 2020; 318(6): C1200 doi: 10.1152/ajpcell.00062.2020
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36 |
Gaelle Fiard, Vasilis Stavrinides, Emma S. Chambers, Susan Heavey, Alex Freeman, Rhys Ball, Arne N. Akbar, Mark Emberton. Cellular senescence as a possible link between prostate diseases of the ageing male. Nature Reviews Urology 2021; 18(10): 597 doi: 10.1038/s41585-021-00496-8
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37 |
Xu-Fei Gao, Bao-Yu Ji, Jun-Jie Zhang, Zi Wang, Shuang Jiang, Jun-Nan Hu, Xiao-Jie Gong, Jing-Tian Zhang, Ivan Stève Nguepi Tsopmejio, Wei Li. Ginsenoside Rg2 Attenuates Aging-Induced Liver Injury via Inhibiting Caspase 8-Mediated Pyroptosis, Apoptosis and Modulating Gut Microbiota. The American Journal of Chinese Medicine 2024; 52(05): 1427 doi: 10.1142/S0192415X24500563
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38 |
Xinhe Lu, Yuhang Luo, Yun Huang, Zhiqiang Zhu, Hongyan Yin, Shunqing Xu. Cellular Senescence in Hepatocellular Carcinoma: Immune Microenvironment Insights via Machine Learning and In Vitro Experiments. International Journal of Molecular Sciences 2025; 26(2): 773 doi: 10.3390/ijms26020773
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39 |
Dechao Feng, Dengxiong Li, Xu Shi, Qiao Xiong, Facai Zhang, Qiang Wei, Lu Yang. A gene prognostic index from cellular senescence predicting metastasis and radioresistance for prostate cancer. Journal of Translational Medicine 2022; 20(1) doi: 10.1186/s12967-022-03459-8
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40 |
Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucher. Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH. Frontiers in Endocrinology 2022; 13 doi: 10.3389/fendo.2022.957616
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41 |
Vassilis G. Giannakoulis, Peter Dubovan, Eleni Papoutsi, Agapi Kataki, John Koskinas. Senescence in HBV-, HCV- and NAFLD- Mediated Hepatocellular Carcinoma and Senotherapeutics: Current Evidence and Future Perspective. Cancers 2021; 13(18): 4732 doi: 10.3390/cancers13184732
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42 |
Lei Sun, Fang‐Hui Li, Chong Han, Zhuang‐Zhi Wang, Ke‐Ke Gao, Yi‐Bo Qiao, Song Ma, Tian Xie, Jing Wang. Alterations in mitochondrial biogenesis and respiratory activity, inflammation of the senescence‐associated secretory phenotype, and lipolysis in the perirenal fat and liver of rats following lifelong exercise and detraining. The FASEB Journal 2021; 35(10) doi: 10.1096/fj.202100868R
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43 |
Ting Yao, Jin‐Mei Chen, Le‐Er Shen, Yong‐Sheng Yu, Zheng‐Hao Tang, Guo‐Qing Zang, Yi Zhang, Xiao‐Hua Chen. Astragalus polysaccharide alleviated hepatocyte senescence via autophagy pathway. The Kaohsiung Journal of Medical Sciences 2022; 38(5): 457 doi: 10.1002/kjm2.12495
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44 |
Christy E. Trussoni, Steven P. O’Hara, Nicholas F. LaRusso. Cellular senescence in the cholangiopathies: a driver of immunopathology and a novel therapeutic target. Seminars in Immunopathology 2022; 44(4): 527 doi: 10.1007/s00281-022-00909-9
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45 |
Ben D. Leaker, Yongtao Wang, Joshua Tam, R. Rox Anderson. Analysis of culture and RNA isolation methods for precision-cut liver slices from cirrhotic rats. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-66235-2
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46 |
Wanvisa Udomsinprasert, Abhasnee Sobhonslidsuk, Jiraphun Jittikoon, Sittisak Honsawek, Usa Chaikledkaew. Cellular senescence in liver fibrosis: Implications for age-related chronic liver diseases. Expert Opinion on Therapeutic Targets 2021; 25(9): 799 doi: 10.1080/14728222.2021.1992385
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47 |
Rhonda D. Kineman, Mercedes del Rio-Moreno, David J. Waxman. Liver-specific actions of GH and IGF1 that protect against MASLD. Nature Reviews Endocrinology 2025; 21(2): 105 doi: 10.1038/s41574-024-01037-0
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48 |
Óscar Brochado, Isidoro Martínez, Juan Berenguer, Luz Medrano, Juan González-García, María Ángeles Jiménez-Sousa, Ana Carrero, Víctor Hontañón, Jordi Navarro, Josep M. Guardiola, Amanda Fernández-Rodríguez, Salvador Resino, A. Carrero, P. Miralles, J. C. López, F. Parras, B. Padilla, T. Aldamiz-Echevarría, F. Tejerina, C. Díez, L. Pérez-Latorre, C. Fanciulli, I. Gutiérrez, M. Ramírez, S. Carretero, J. M. Bellón, J. Bermejo, J. Berenguer, V. Hontañón, J. R. Arribas, M. L. Montes, I. Bernardino, J. F. Pascual, F. Zamora, J. M. Peña, F. Arnalich, M. Díaz, J. González-García, P. Domingo, J. M. Guardiola, E. Van den Eynde, M. Pérez, E. Ribera, M. Crespo, J. L. Casado, F. Dronda, A. Moreno, M. J. Pérez-Elías, M. A. Sanfrutos, S. Moreno, C. Quereda, A. Arranz, E. Casas, J. de Miguel, S. Schroeder, J. Sanz, J. Sanz, I. Santos, M. J. Bustinduy, J. A. Iribarren, F. Rodríguez-Arrondo, M. A. Von-Wichmann, J. Vergas, M. J. Téllez, D. Vinuesa, L. Muñoz, J. Hernández-Quero, A. Ferrer, M. J. Galindo, L. Ortiz, E. Ortega, M. Montero, M. Blanes, S. Cuellar, J. Lacruz, M. Salavert, J. López-Aldeguer, G. Pérez, G. Gaspar, M. Yllescas, P. Crespo, E. Aznar, H. Esteban. HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients. Journal of Biomedical Science 2021; 28(1) doi: 10.1186/s12929-021-00718-6
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Yuxiang Du, Liwei Mao, Zhikun Wang, Kai Yan, Lingli Zhang, Jun Zou. Osteopontin - The stirring multifunctional regulatory factor in multisystem aging. Frontiers in Endocrinology 2022; 13 doi: 10.3389/fendo.2022.1014853
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Yuki Takamatsu, Sanae Hayashi, Hiroki Kumamoto, Shuhei Imoto, Yasuhito Tanaka, Hiroaki Mitsuya, Nobuyo Higashi-Kuwata. A novel anti-HBV agent, E-CFCP, restores Hepatitis B virus (HBV)-induced senescence-associated cellular marker perturbation in human hepatocytes. Virus Research 2023; 329: 199094 doi: 10.1016/j.virusres.2023.199094
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51 |
Nikolaos-Andreas Anastasopoulos, Antonia V. Charchanti, Alexandra Barbouti, Eleftheria M. Mastoridou, Anna C. Goussia, Anastasia D. Karampa, Dimitrios Christodoulou, Georgios K. Glantzounis. The Role of Oxidative Stress and Cellular Senescence in the Pathogenesis of Metabolic Associated Fatty Liver Disease and Related Hepatocellular Carcinoma. Antioxidants 2023; 12(6): 1269 doi: 10.3390/antiox12061269
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52 |
Yuki Tamaki, Yuria Shibata, Misaki Hayakawa, Nodoka Kato, Ami Machii, Yuma Ikeda, Eri Nanizawa, Yumi Hayashi, Hiroshi Suemizu, Hiroyasu Ito, Tetsuya Ishikawa. Treatment with hepatocyte transplantation in a novel mouse model of persistent liver failure. Biochemistry and Biophysics Reports 2022; 32: 101382 doi: 10.1016/j.bbrep.2022.101382
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53 |
Nazmul Huda, Bilon Khambu, Gang Liu, Hirokazu Nakatsumi, Shengmin Yan, Xiaoyun Chen, Michelle Ma, Zheng Dong, Keiichi I. Nakayama, Xiao-Ming Yin. Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver. Cellular and Molecular Gastroenterology and Hepatology 2022; 14(2): 333 doi: 10.1016/j.jcmgh.2022.04.003
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54 |
Peter M. Abuja, Kurt Zatloukal, Helmut Denk. Priming, Triggering, Adaptation and Senescence (PTAS): A Hypothesis for a Common Damage Mechanism of Steatohepatitis. International Journal of Molecular Sciences 2021; 22(22): 12545 doi: 10.3390/ijms222212545
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Medine Zeynep Gungor, Merve Uysal, Serif Senturk. The Bright and the Dark Side of TGF-β Signaling in Hepatocellular Carcinoma: Mechanisms, Dysregulation, and Therapeutic Implications. Cancers 2022; 14(4): 940 doi: 10.3390/cancers14040940
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56 |
Claire E. McQuitty, Roger Williams, Shilpa Chokshi, Luca Urbani. Immunomodulatory Role of the Extracellular Matrix Within the Liver Disease Microenvironment. Frontiers in Immunology 2020; 11 doi: 10.3389/fimmu.2020.574276
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57 |
M. M. Heldring, A. H. Shaw, J. B. Beltman. Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury. npj Systems Biology and Applications 2022; 8(1) doi: 10.1038/s41540-022-00238-5
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58 |
Shanshan Yang, Chengyu Liu, Mengmeng Jiang, Xiaoqian Liu, Lingling Geng, Yiyuan Zhang, Shuhui Sun, Kang Wang, Jian Yin, Shuai Ma, Si Wang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu. A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes. Protein & Cell 2024; 15(2): 98 doi: 10.1093/procel/pwad039
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59 |
Hyun-Ju Park, Juyong Choi, Hyunmi Kim, Da-Yeon Yang, Tae Hyeon An, Eun-Woo Lee, Baek-Soo Han, Sang Chul Lee, Won Kon Kim, Kwang-Hee Bae, Kyoung-Jin Oh. Cellular heterogeneity and plasticity during NAFLD progression. Frontiers in Molecular Biosciences 2023; 10 doi: 10.3389/fmolb.2023.1221669
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60 |
Su-Jeong Lee, Da-Yeon Lee, Jennifer F. O’Connell, Josephine M. Egan, Yoo Kim. Black Ginseng Ameliorates Cellular Senescence via p53-p21/p16 Pathway in Aged Mice. Biology 2022; 11(8): 1108 doi: 10.3390/biology11081108
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61 |
Li Gu, Yahui Zhu, Shuvro P. Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng, Masafumi Ohira, Yuxiao Liu, Sadatsugu Sakane, Rodrigo Carlessi, Consuelo Sauceda, Debanjan Dhar, Souradipta Ganguly, Mojgan Hosseini, Marcos G. Teneche, Peter D. Adams, David J. Gonzalez, Tatiana Kisseleva, Janina E. E. Tirnitz-Parker, Peter J. Leedman, Michael C. Wallace, Louise N. Winteringham, Benjamin J. Dwyer, Jonathan Tibballs, Kim W. Carter, Alistair R. R. Forrest, Janina E. E. Tirnitz-Parker, M. Celeste Simon, Ludmil B. Alexandrov, Michael Karin. FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature 2025; 637(8045): 461 doi: 10.1038/s41586-024-08317-9
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