European vs 2015-World Health Organization clinical molecular and pathological classification of myeloproliferative neoplasms

Figure 5 Spectrum of essential thrombocythemia and polycythemia vera bone marrow features in 155 bone marrow biopsies with clustered large pleomorphic megakaryocytes in polycythemia vera patients from the polycythemia vera study group 01 study. ET bone marrow histology (A and C): arrows indicate clustered pleiomorphic megakaryocytes. PV (B) with trilinear megakaryo/eryhtro/granulocytic hyperplasia. Source Ellis et al[41] polycythemia vera study group 1975 and Wasserman et al[49]. An ET picture was observed in 10 PV. An ET/PV bone marrow picture with increased cellularity (60%-80%, D) was detected in 45 PV. A hypercellular (80%-100%, B) PV picture was recorded in 90 bone marrow biopsies of 155 PV patients the PVSG 01 study. PV: Polycythemia vera; ET: Essential thrombocythemia.