Advances in cardiovascular-related biomarkers to predict diabetic peripheral neuropathy

doi:10.4239/wjd.v14.i8.1226

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Aug 15, 2023 (publication date) through May 31, 2024

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World Journal of Diabetes

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World J Diabetes. Aug 15, 2023; 14(8): 1226-1233
Published online Aug 15, 2023. doi: 10.4239/wjd.v14.i8.1226

Advances in cardiovascular-related biomarkers to predict diabetic peripheral neuropathy

Meng-Ke Cheng, Yao-Yao Guo, Xiao-Nan Kang, Lu Zhang, Dan Wang, Hui-Hui Ren, Gang Yuan

Meng-Ke Cheng, Yao-Yao Guo, Xiao-Nan Kang, Lu Zhang, Dan Wang, Hui-Hui Ren, Gang Yuan, Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, Hubei Province, China

Author contributions: All authors made a substantial contribution to conceptualization and writing and agree to be accountable for the content of this review.

Supported by National Natural Science Foundation of China, No. 82100922.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Gang Yuan, MD, PhD, Professor, Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, No. 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. gangyuan@tjh.tjmu.edu.cn

Received: May 31, 2023
Peer-review started: May 31, 2023
First decision: June 13, 2023
Revised: June 24, 2023
Accepted: July 7, 2023
Article in press: July 7, 2023
Published online: August 15, 2023

Core Tip

Core Tip: Emerging evidence indicates that traditional and novel cardiovascular-related biomarkers have the potential to characterize patients by subclinical disease status and improve risk prediction. Additionally, beyond traditional cardiovascular-related biomarkers, novel cardiovascular-related biomarkers have been linked to diabetes and its complications. In this paper, we review the association between major traditional and nontraditional cardiovascular-related biomarkers and diabetic peripheral neuropathy (DPN) and assess the evidence for early risk factor-based management strategies to reduce the incidence and slow the progression of DPN.