Effect of dl-3-n-butylphthalide on infarction volume in animal models of ischemic stroke: A meta-analysis

Figure 1 Literature inclusion flow chart. NBP: Dl-3-n-butylphthalide; MCAO: Middle cerebral artery occlusion.

Figure 2 The forest plot: Effects of dl-3-n-butylphthalide for decreasing the cerebral infarction volume compared with control group.

Figure 3 The forest plot: Effects of dl-3-n-butylphthalide for decreasing the cerebral infarction volume compared with control group in transient (A) and permanent (B) middle cerebral artery occlusion model, respectively.

Figure 4 The forest plot: Effects of dl-3-n-butylphthalide for decreasing the cerebral infarction volume compared with control group in pre (A) and post-administration (B) model, respectively.

Figure 5 The funnel plot evaluation publication bias and underlying mechanism of dl-3-n-butylphthalide in neuroprotection. A: The funnel plot evaluation publication bias for the dl-3-n-butylphthalide on infarction volume; B: The underlying mechanism of dl-3-n-butylphthalide in neuroprotection.