Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. May 31, 2019; 7(5): 184-208
Published online May 31, 2019. doi: 10.13105/wjma.v7.i5.184
Current state and future direction of screening tool for colorectal cancer
Ji Taek Hong, Eun Ran Kim
Ji Taek Hong, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon 24253, South Korea
Eun Ran Kim, Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, South Korea
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Eun Ran Kim, MD, Staff Physician, Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea. er.kim@samsung.com
Telephone: +82-2-34103409 Fax: +82-2-34106983
Received: March 18, 2019
Peer-review started: March 19, 2019
First decision: May 18, 2019
Revised: May 25, 2019
Accepted: May 27, 2019
Article in press: May 28, 2019
Published online: May 31, 2019
Processing time: 74 Days and 15.1 Hours
Core Tip

Core tip: A large proportion of colorectal cancer (CRC) cases and deaths could be prevented by screening with early detection and removal of colorectal adenomas or early stage CRC. Reliable and non-invasive screening tools for early stage CRC and precancerous lesions, such as adenoma is indispensable. However, current screening methods have limitations. Therefore, it is important to review the current literature on new screening tools such as molecular biomarkers and metabolomics for the development of new diagnostic tools.