Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Jun 26, 2015; 3(3): 181-187
Published online Jun 26, 2015. doi: 10.13105/wjma.v3.i3.181
Sleep-associated movement disorders and the risk of cardiovascular disease: A systematic review and meta-analysis
Zhen Fang, Yao-Wu Liu, Li-Yan Zhao, Yan Xu, Feng-Xiang Zhang
Zhen Fang, Yao-Wu Liu, Li-Yan Zhao, Yan Xu, Feng-Xiang Zhang, Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: Fang Z, Liu YW and Zhang FX designed the review; Fang Z, Zhao LY and Xu Y collected the data; Fang Z and Liu YW analyzed the data and wrote the paper.
Supported by The National Natural Science Foundation of China, Nos. 81470456 and 81170160; The priority Academic Program Development of Jiangsu Higher Education Institutions.
Conflict-of-interest: No conflict of interest.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Feng-Xiang Zhang, MD, PhD, Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing 210029, Jiangsu Province, China. njzfx6@njmu.edu.cn
Telephone: +86-25-68136056 Fax: +86-25-83717168
Received: January 25, 2015
Peer-review started: January 27, 2015
First decision: February 7, 2015
Revised: April 9, 2015
Accepted: April 16, 2015
Article in press: April 20, 2015
Published online: June 26, 2015
Processing time: 156 Days and 0.4 Hours
Core Tip

Core tip: We conducted a meta-analysis of 13 relevant studies to investigate the association between sleep-associated movement disorders and cardiovascular disease (CVD). The present study suggested that sleep-associated movement disorders are associated with prevalence of CVD. This finding indicates that sleep-associated movement disorders may prove to be predictive of underlying CVD.