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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Nov 26, 2014; 2(4): 162-170
Published online Nov 26, 2014. doi: 10.13105/wjma.v2.i4.162
Published online Nov 26, 2014. doi: 10.13105/wjma.v2.i4.162
Diagnostic yield of third eye retroscope on adenoma detection during colonoscopy: A systematic review and meta-analysis
Nirav Thosani, Bhavana Rao, Sachin Batra, Babatunde Adeyefa, Sushovan Guha, Division of Gastroenterology, Hepatology and Nutrition, The University of Texas Medical School, Houston, TX 77030, United States
Nirav Thosani, Gottumukkala S Raju, Robert S Bresalier, Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States
Nirav Thosani, Subhas Banerjee, Department of Gastroenterology, Stanford University, Stanford, California, CA 94305, United States
Author contributions: Thosani N contributed to concept and study design, acquisition of data, analysis and interpretation of data, drafting of manuscript, critical revision of manuscript for important intellectual content, statistical analysis and technical support; Rao B contributed to acquisition of data and drafting of manuscript; Batra S contributed to acquisition of data, analysis and interpretation of data, revision of manuscript, statistical analysis, and drafting of manuscript; Adeyefa B contributed to acquisition of data and drafting of manuscript; Raju GS, Bresalier RS and Banerjee S contributed to analysis and interpretation of data and critical revision of manuscript for important intellectual content; Guha S contributed to concept and study design, analysis and interpretation of data, drafting of manuscript, critical revision of manuscript for important intellectual content, statistical analysis, administrative, technical, or material support and supervision.
Correspondence to: Nirav Thosani, MD, MHA, Division of Gastroenterology, Hepatology and Nutrition, The University of Texas Medical School, MSB 4.234, 6431 Fannin Street, Houston, TX 77030, United States. ncthosani@gmail.com
Telephone: +1-713-5006677 Fax: +1-713-5006699
Received: June 1, 2014
Revised: September 20, 2014
Accepted: October 14, 2014
Published online: November 26, 2014
Processing time: 184 Days and 0.2 Hours
Revised: September 20, 2014
Accepted: October 14, 2014
Published online: November 26, 2014
Processing time: 184 Days and 0.2 Hours
Core Tip
Core tip: Missed lesions remain one of the main causes for development of interval colorectal cancer after screening colonoscopy. The third eye retroscope (TER) provides an additional retrograde view to visualize lesions on the proximal aspects of folds. In this meta-analysis of four studies including 920 patients undergoing screening colonoscopy, we observed that the additional adenoma detection rate, defined as the number of additional adenomas identified due to TER device in comparison to standard colonoscopy alone, was 19.9% (95%CI: 7.3-43.9). We found that TER device was safe and identified significant more numbers of adenoma which would have been missed by standard colonoscopy alone.