Mirghani HO. Diabetes distress, the mediator of the poor glycemic control and depression: A meta-analysis. World J Meta-Anal 2024; 12(4): 97779 [DOI: 10.13105/wjma.v12.i4.97779]
Corresponding Author of This Article
Hyder O Mirghani, MD, Professor, Department of Internal Medicine, University of Tabuk, Prince Fahd Bin Sultan, Tabuk 51941, Tabuk Province, Saudi Arabia. s.hyder63@hotmail.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Meta-Anal. Dec 18, 2024; 12(4): 97779 Published online Dec 18, 2024. doi: 10.13105/wjma.v12.i4.97779
Diabetes distress, the mediator of the poor glycemic control and depression: A meta-analysis
Hyder O Mirghani
Hyder O Mirghani, Department of Internal Medicine, University of Tabuk, Tabuk 51941, Tabuk Province, Saudi Arabia
Author contributions: Mirghani HO performed the conception and design of the study, and the literature search, performed the drafting and critical revision of the manuscript and provided the final approval of the version to be published.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyder O Mirghani, MD, Professor, Department of Internal Medicine, University of Tabuk, Prince Fahd Bin Sultan, Tabuk 51941, Tabuk Province, Saudi Arabia. s.hyder63@hotmail.com
Received: June 8, 2024 Revised: November 1, 2024 Accepted: December 5, 2024 Published online: December 18, 2024 Processing time: 187 Days and 5.5 Hours
Core Tip
Core Tip: Literature on the effects of diabetes distress is scarce, the available meta-analyses focused on interventions to tackle diabetes (to improve glycemic control) distress instead of investigating the direct influence of diabetes distress on the same. However, the association of depression with glycemic control was touched before. However, this is the first meta-analysis to compare the effects of diabetes distress and depression on glycated hemoglobin (HbA1c). We found an association between diabetes distress, depression, and HbA1c with a higher impact of distress arm compared to depression. Due to the overlap between the symptoms of diabetes distress and depression, diabetes distress could mediate the association between depression and HbA1c. Although the reverse could be true, diabetes distress is commoner than depression. The current findings challenged the scientific community and recommended screening for both diabetes distress and depression among patients with diabetes mellitus and poor glycemic control. In addition, we suggested future studies using continuous glucose monitoring and ecological momentary assessment to evaluate the association of diabetes distress, depression, and glycemic control.
