Fazio S, Affuso F. Opinion on double strategy to fight against COVID-19: Vaccination and home treatment with non-steroidal anti-inflammatory drugs. World J Meta-Anal 2023; 11(1): 1-4 [DOI: 10.13105/wjma.v11.i1.1]
Corresponding Author of This Article
Serafino Fazio, MD, retired Associate Professor, Department of Internal Medicine, Federico II university of Naples, via Sergio Pansini 5, Napoli 80100, Italy. fazio0502@gmail.com
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Opinion Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Author contributions: Affuso F, and Fazio S contributed equally to this work; both authors have read and approved the final manuscript.
Conflict-of-interest statement: Flora Affuso and Serafino Fazio have no competing conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Serafino Fazio, MD, retired Associate Professor, Department of Internal Medicine, Federico II university of Naples, via Sergio Pansini 5, Napoli 80100, Italy. fazio0502@gmail.com
Received: October 24, 2022 Peer-review started: October 24, 2022 First decision: November 2, 2022 Revised: November 7, 2022 Accepted: December 23, 2022 Article in press: December 23, 2022 Published online: January 12, 2023 Processing time: 78 Days and 13.6 Hours
Core Tip
Core Tip: The goals of global vaccination are to control, eliminate, or eradicate infectious diseases in a sustainable way that strengthens public health systems. Although the use of vaccines is essential for the control of epidemics, the vaccines against coronavirus disease 2019 (COVID-19) proved to be inadequate to end the pandemic and thus are considered incomplete. These vaccines failed to prevent infection, so their primary purpose now has been shifted to prevent severe disease and reduce hospitalizations and deaths. Therefore, we believe that all the strategies available to reduce transmission, hospitalizations and deaths due to COVID-19 will be put in place. In this regard, many observational studies have constantly shown beneficial effects of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with low to moderate degree of COVID-19, in particular when administered within the first 72 h of symptom onset. Randomized controlled studies with NSAIDs should be carried out as soon as possible to confirm these results.
