Published online May 31, 2019. doi: 10.13105/wjma.v7.i5.224
Peer-review started: April 3, 2019
First decision: April 30, 2019
Revised: May 11, 2019
Accepted: May 22, 2019
Article in press: May 26, 2019
Published online: May 31, 2019
Processing time: 58 Days and 20.9 Hours
A minor subset of primary gastrointestinal stromal tumors (GIST) can also arise outside the gastrointestinal tract, which is known as an extra-GIST (E-GIST).
Primary GIST of the liver is an exceptional location and this study aimed to characterize epidemiological, clinical and pathological features and options of treatments.
Our aim is to characterize epidemiological, clinical and pathological features and options of treatments.
We perform a system review including all patients with hepatic GISTs.
This review shows that right hepatic lobe was the most frequent location, the median size was higher, there was a Southeast Asian predominance, and nearly 50% of patients have no symptoms. The most frequent treatment was surgery and more than 70% of patients had a lesion with high risk of malignancy.
Literature on hepatic EGIST is scarce and further studies such as multicentric databases are needed to clarify diagnosis and treatment.