Effects of transjugular intrahepatic portosystemic shunt using the Viatorr stent on hepatic reserve function in patients with cirrhosis

Table 1 Basic clinical data

Clinical factor	Hepatitis cirrhosis (n = 71)	Alcoholic cirrhosis (n = 67)	Autoimmune cirrhosis (n = 62)	Statistic	P value
Gender (n)				χ2 = 3.43	0.18
Male	46	42	31
Female	25	25	31
Age (yr, mean ± SD)	55.5 ± 8.7	54.7 ± 8.5	55.3 ± 9.6	F = 0.15	0.87
Child-Pugh Classification				χ2 = 3.19	0.53
A	32	25	19
B	34	35	37
C	5	7	6
Child-Pugh score	7.25 ± 1.54	7.55 ± 1.45	7.48 ± 1.29	F = 0.82	0.44
MELD score	10.24 ± 3.52	9.67 ± 2.90	10.47 ± 2.97	F = 1.11	0.33
Prothrombin time (s)	14.59 ± 2.79	14.98 ± 2.46	14.74 ± 2.92	F = 0.36	0.69
ALT (IU/L)	35.28 ± 16.40	37.75 ± 12.17	36.95 ± 10.82	F = 0.42	0.67
AST (IU/L)	48.87 ± 24.43	50.13 ± 23.10	50. 75 ± 24.34	F = 0.06	0.94
Albumin (g/L)	35.09 ± 6.33	34.14 ± 4.52	34.23 ± 4.44	F = 0.69	0.50
Total bilirubin (μmol/L)	33.53 ± 12.99	32.75 ± 14.88	32.47 ± 16.84	F = 0.04	0.96
PPG before TIPS (mmHg)	24.58 ± 4.79	25.45 ± 5.16	25.27 ± 5.65	F = 1.78	0.17
PPG after TIPS (mmHg)	9.94 ± 2.55	10.22 ± 3.07	10.01 ± 2.65	F = 0.22	0.80
Deaths in 24 mo, n (%)	8 (11.3)	12 (17.9)	9 (14.5)	χ2 = 1.23	0.54
HE in 24 mo, n (%)	15 (21.1)	17 (25.4)	18 (29.0)	χ2 = 1.11	0.57

MELD: Model for end-stage liver disease; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TIPS: Transjugular intrahepatic portosystemic shunt; PPG: Portal pressure gradient; HE: Hepatic encephalopathy.

Table 2 Child-Pugh constituent ratio

	Baseline	1 wk	1 mo	3 mo	6 mo	12 mo	24 mo
Hepatitis cirrhosis (n)	18/45/8 (71)	14/46/11 (71)	10/52/9 (71)	9/53/9 (71)	16/49/5 (70)	23/42/3 (68)	34/28/1 (63)
Child-Pugh A/B/C (%)	25.4/63.4/11.3	19.7/64.8/15.5	14.1/73.2/12.7	12.7/74.6/12.7	22.9/70.0/7.1	33.8/61.8/4.4	54.0/44.4/1.6
Alcoholic cirrhosis (n)	14/46/7 (67)	7/52/8 (67)	8/51/8 (67)	6/49/12 (67)	12/45/8 (65)	15/41/5 (61)	13/37/5 (55)
Child-Pugh A/B/C (%)	20.8/68.7/10.4	10.4/77.6/11.9	11.9/76.1/12.0	8.9/73.2/17.9	18.5/69.2/12.3	24.6/67.2/8.2	23.6/67.3/9.1
Autoimmune cirrhosis (n)	12/45/5 (62)	7/49/6 (62)	10/43/8(61)	8/41/12 (61)	11/43/6 (60)	13/43/2 (58)	14/35/4 (53)
Child-Pugh A/B/C (%)	19.4/72.6/8.1	11.3/79.0/9.7	16.4/70.5/13.1	13.1/67.2/19.7	18.3/71.7/10.0	22.4/74.1/3.5	26.4/66.1/7.5