Case Report
Copyright ©The Author(s) 2021.
World J Clin Cases. Feb 26, 2021; 9(6): 1386-1393
Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1386
Table 1 Laboratory values at start of treatment with D-penicilliamine
Date of testing
ALT (U/L)
AST (U/L)
GGT (U/L)
Non-CP-bound copper (µg/dL)
08/09114652827
10/09113553021
03/1061432716
06/10283120< 15
10/10332721< 15
12/10242519< 15
03/11192418< 15
10/11172513< 15
Table 2 Increase of transaminases during different chelator therapies
Therapy
Date of testing
ALT (U/L)
AST (U/L)
GGT (U/L)
Non-CP-bound copper (µg/dL)
Trientine-2HCl02/163824< 40< 15
03/164728< 40< 15
07/164430< 40< 15
09/164230< 40< 15
10/163921< 40< 15
11/173424< 40< 15
05/173924< 40< 15
10/175630< 40< 15
Trientine-2HCl + zinc01/186936< 40< 15
04/182423< 40< 15
08/184140< 40< 15
10/186630< 40< 15
Trientine-2HCl05/1917461ND< 15
Trientine-4HCl07/192457451< 10
08/192858076< 15
09/192979067< 15
10/193678187< 15
11/1941710776< 15
D-penicillamine04/12/1950512879< 15
10/12/1957114777< 15
17/12/1940910978< 15
D-penicillamine+Prednisolone
40 mg15/01/2041613559< 15
40 mg30/01/202687956< 15
20 mg18/02/201704754< 15
5 mg15/03/20843733< 15
D-penicillamine alone125/03/2016860ND< 15
20/4/2011748
29/5/2012746