Copyright
©The Author(s) 2021.
World J Clin Cases. Sep 6, 2021; 9(25): 7498-7503
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7498
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7498
Table 1 Somatic mutation and germline mutation detected by next-generation sequencing
| Somatic mutation | ||||
| Gene | Transcript | c.HGVS | p.HGVS | Allele frequency |
| ASXL1 | NM_015338.5 | c.2247C[4>3] | p.V751Lfs*21 | 0.6% |
| Germline mutation | ||||
| Gene | Transcript | c.HGVS | p.HGVS | Homozygous/heterozygous |
| BRCA2 | NM_000059.3 | c.6816_6820delAAGAG | p.G2274Afs*17 | Heterozygous |
- Citation: Zhang L, Wang J, Cui LZ, Wang K, Yuan MM, Chen RR, Zhang LJ. Successful treatment of refractory lung adenocarcinoma harboring a germline BRCA2 mutation with olaparib: A case report. World J Clin Cases 2021; 9(25): 7498-7503
- URL: https://www.wjgnet.com/2307-8960/full/v9/i25/7498.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i25.7498