S-1 plus temozolomide as second-line treatment for neuroendocrine carcinoma of the breast: A case report

Table 1 Timeline

April 2012	July 2012	2012-2016	October 2016	October 2016	November 2016-March 2017	October 2017-July 2019
Feel pain of the right breast	Right-sided modified radical mastectomy. Diagnosis of neuroendocrine carcinoma of the breast	Endocrine therapy + regular follow-up	Intermittent nausea, vomiting and diarrhea; multiple masses in the liver found on routine abdominal CT imaging	Diagnosis of neuroendocrine carcinoma of the breast stage IV with liver, lung, and bone metastases	Etoposide and cisplatin chemotherapyfor 6 cycles	S-1 combined with temozolomide chemotherapy
	Local hospital	Local hospital		Our hospital	Our hospital	Our hospital

CT: Computed tomography.