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©The Author(s) 2021.
World J Clin Cases. Aug 26, 2021; 9(24): 7073-7084
Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.7073
Published online Aug 26, 2021. doi: 10.12998/wjcc.v9.i24.7073
Study | Area | Study type | Peptic ulcer (Hp+/Hp-) | Prevalence | Non-ulcer (Hp+/Hp-) | Prevalence | D of Hp | D of LC |
Wu et al[11], 1995 | Asia | Cross-sectional | 23/6 | 82.1% | 59/32 | 64.8% | ELISA | Ultrosound |
Kim et al[13], 2008 | Asia | Cross-sectional | 24/46 | 34.3% | 76/142 | 34.9% | Multiple | Multiple |
Siringo et al[12], 1997 | Europe | Cross-sectional | 39/2 | 95.1% | 78/34 | 69.4% | ELISA | Multiple |
Kirchner et al[10], 2011 | Europe | Cross-sectional | 11/7 | 61.1% | 65/27 | 70.7% | ELISA | Multiple |
Voulgaris et al[16], 2019 | Europe | Cross-sectional | 9/10 | 47.4% | 45/36 | 55.6% | Multiple | Multiple |
Wang et al[15], 1997 | Asia | Cross-sectional | 12/18 | 40.0% | 7/12 | 36.8% | Multiple | Multiple |
Chen et al[17], 1994 | Asia | Cross-sectional | 14/17 | 45.2% | 33/44 | 42.9% | ELISA | Multiple |
Chen et al[18], 1995 | Asia | Cross-sectional | 9/7 | 56.3% | 18/16 | 52.9% | RUT | Multiple |
Yeh et al[19], 2001 | Asia | Cohort | 26/19 | 57.8% | 31/33 | 48.4% | UBT | Multiple |
Hu et al[20], 2002 | Asia | Cross-sectional | 86/8 | 91.5% | 373/189 | 66.4% | Multiple | Multiple |
Tuo et al[21], 2000 | Asia | Cross-sectional | 29/45 | 39.2% | 143/279 | 33.9% | Multiple | Multiple |
Calvet et al[14], 1998 | Europe | Cross-sectional | 14/6 | 70.0% | 79/91 | 46.5% | Multiple | Multiple |
Zullo et al[9], 1999 | Europe | Cross-sectional | 51/9 | 85.0% | 84/82 | 50.6% | Multiple | Multiple |
Tsai[5], 1998 | Asia | Cross-sectional | 54/10 | 84.4% | 46/20 | 69.7% | Multiple | Multiple |
Subcategory | Random-effects model | Meta-regression | |||||
n | OR (95%CI) | P value | I2 | Ajusted-R2 | P value | χ2 | |
Year | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | 4.64% | 0.241 | 33.29% |
Before 2000 | 8 | 2.19 (1.31-3.67) | 0.039 | 52.60% | |||
After 2000 (2000) | 6 | 1.34 (0.75-2.38) | 0.02 | 73.50% | |||
Area | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -5.48% | 0.467 | 36.82% |
Asia | 9 | 2.19 (0.81-5.97) | 0.001 | 79.0% | |||
Europe | 5 | 1.67 (0.56-4.97) | 0.09 | 74% | |||
Study type | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -14.28% | 0.817 | 39.89% |
Cross-sectional study | 13 | 1.75 (1.14-2.70) | < 0.01 | 68.7% | |||
Cohort study | 1 | 1.46 (0.68-3.14) | |||||
Diagnosis of Hp | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -13.83% | 0.935 | 39.73% |
ELISA | 4 | 1.52 (0.62-3.74) | 0.036 | 64.80% | |||
Multiple | 8 | 1.95 (1.12-3.39) | 0.003 | 75.30% | |||
RUT | 1 | 1.14 (0.35-3.78) | |||||
UBT | 1 | 1.46 (0.68-3.14) | |||||
Diagnosis of liver cirrhosis | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -11.75% | 0.817 | 39.01% |
Ultrasound | 1 | 1.43 (0.51-3.98) | |||||
Multiple | 13 | 1.75 (1.15-2.67) | < 0.01 | 68.70% | |||
Case/control ratio | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -14.36% | 0.787 | 39.92% |
≥ 0.3 | 9 | 1.80 (1.11-2.90) | 0.009 | 60.60% | |||
< 0.3 | 5 | 1.59 (0.73-3.47) | 0.001 | 77.90% | |||
Sample size | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | 5.11% | 0.24 | 33.12% |
≥ 100 | 12 | 1.89 (1.23-2.91) | < 0.01 | 68.70% | |||
< 100 | 2 | 0.87 (0.40-1.88) | 0.5611 | ||||
Language | 14 | 1.73 (1.16-2.56) | < 0.01 | 66.20% | -7.60% | 0.439 | 37.56% |
English | 12 | 1.59 (1.05-2.42) | 0.005 | 58.7% | |||
Chinese | 2 | 2.55 (0.58-11.14) | 0.001 | 90.6% |
- Citation: Wei L, Ding HG. Helicobacter pylori infection and peptic ulcer disease in cirrhotic patients: An updated meta-analysis. World J Clin Cases 2021; 9(24): 7073-7084
- URL: https://www.wjgnet.com/2307-8960/full/v9/i24/7073.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i24.7073