Li M, Li N. Clostridium perfringens bloodstream infection secondary to acute pancreatitis: A case report. World J Clin Cases 2021; 9(17): 4357-4364 [PMID: 34141801 DOI: 10.12998/wjcc.v9.i17.4357]
Corresponding Author of This Article
Ming Li, MS, Department of Hepatopancreatobiliary Surgery, Integrated Chinese and Western Medicine Hospital, Tianjin University, No. 6 Changjiang Road, Tianjin 300000, China. lm_peasant@126.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
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World J Clin Cases. Jun 16, 2021; 9(17): 4357-4364 Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4357
Table 1 Comparison of blood tests between the two admissions
Second admission
First admission
Normal range
White blood cells (109/L)
29.50
15.83
4-10
Red blood cells (1012/L)
1.88
4.28
3.5-5.5
Hemoglobin (g/L)
64
132
110-160
Hematocrit (%)
13.5
38.4
37-49
Mean corpuscular volume (fL)
71.8
89.7
80-100
Mean corpuscular hemoglobin (pg)
34
30.9
27-32
Mean corpuscular hemoglobin concentration (g/L)
474
344
320-360
Platelets (109/L)
95
181
100-300
Table 2 Liver function at the second admission
Second admission
Normal range
Total protein (g/L)
118.6
60-80
Albumin (g/L)
56.1
35-55
Prealbumin (mg/L)
96
200-400
Total bilirubin (µmol/L)
128.3
5.1-20.4
Direct bilirubin (µmol/L)
86.3
1.7-6.8
Total bile acid (µmol/L)
30.9
1-7
Alkaline phosphatase (U/L)
430
34-114
γ-glutaryl transferase (U/L)
481
11-50
Alanine transaminase (U/L)
310
5-40
Table 3 Serum electrolytes
Second admission
Normal range
Sodium (mmol/L)
135.6
135-145
Potassium (mmol/L)
3.95
3.6-5.5
Chlorinum (mmol/L)
102.1
96-106
Table 4 Summary of the clinical course
Time
Event
January 8
16:30
First admission to the emergency room
17:00-18:00
Urine amylase at 10403 U/L (normal: 47-458), first CT, first blood routine test, blood amylase at 1006 U/L (normal: < 100)
The end
Refused hospitalization, anti-pancreatitis treatment in the emergency room
January 9
11:00
Second admission to the emergency room
12:00
Hospitalization, walked into the general ward
13:45
Consciousness disturbance, oxygen saturation 77%
14:30
Consciousness recovered a little, oxygen saturation 90%
16:00
Second CT on the way to the ICU
17:12
Second blood routine test, liver function
21:42
High fever of 40 °C, blood culture
22:18
Cefoperazone/sulbactam was administered
January 10
00:30
Cardiac arrest
01:30
Death
January 13
10:40
The result of the blood culture confirmed Clostridium perfringens infection
Citation: Li M, Li N. Clostridium perfringens bloodstream infection secondary to acute pancreatitis: A case report. World J Clin Cases 2021; 9(17): 4357-4364