Case Report
Copyright ©The Author(s) 2021.
World J Clin Cases. Jun 16, 2021; 9(17): 4327-4335
Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4327
Table 1 Summary of pancreatic neuroendocrine neoplasms in pregnancy (2000-2019)
Ref.
Patient age
Onset of symptoms
Symptoms
Management
Maternal outcomes
Fatal outcomes
Fredericks et al[19]35-yr-old Three weeks post-partumNeuroglycopaenic symptomsLaparotomy the tumorNo symptoms after removalLive born
Takacs et al[20]28-yr-oldAt 6-wk gestationDifficult morning arousabilityExploratory laparotomyNo residual symptomsCesarean delivery
Live born
Lowy and Chisholm[23]36-yr-oldTwelve hours post-partumSevere hypoglycaemiaExcision of the lesionNo symptoms after removalLive born
Diaz et al[24]35-yr-oldThree monthsLoss of consciousnessExploratory laparotomyNo residual symptomsLive born
Post-partum
Diaz et al[24]35-yr-oldOn the 26th postpartum dayConfusion, dysarthria, and quadriplegiaEnucleation of an 8-mm tumorNo symptoms after removalLive born
Diaz et al[24]22-yr-oldAt 2-mo gestationLoss of consciousnessLaparoscopic distal pancreatectomyNo residual symptomsNatural labor
Post-partumLive born
Christiansen and Vestergaard[25]29-yr-oldAt 38-mo gestationSlurred speech, weaknessPancreaticoduodenectomy and cholecystectomyNo symptoms after removalNatural labor
Post-partumLive born
Rodrigues Queiróz et al[26]21-yr-oldEight days post-partum Four limbs weahness, diffic-ult walkingPancreatectomyNo residual symptomsLive born
Mannelli et al[27]29-yr-oldAt 17 wk gestationSevere hypoglycemiaStarted therapy with everolimusDied 3 yr after deliveryCesareandelivery
Live born
Tomazic et al[28]36-yr-oldIn the second trimester of pregnancyHypoglycemia associated with neuroglycopenic symptomsDistal pancreatectomy at 21 wk gestationNo symptoms after removalNature labor
Live born