Case Report
Copyright ©The Author(s) 2021.
World J Clin Cases. Apr 6, 2021; 9(10): 2302-2311
Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2302
Table 1 Case report timeline
Complaint/investigations
Details
Presenting symptomsDull pain and protruding mass for 3 mo; Nocturnal pain; Mass gradually increased in size; Overhead arm elevation limitation
CTFocal osteoblastic change in sternum manubrium region with bony exostosis with adjacent soft tissue calcification mass
PET-CTMass with hypermetabolic activity over the upper sternum
Bone scintigraphyFocal increased uptake over the upper sternum
MRIFocal ill-defined bony mass of the sternum with cortical destruction and periosteal reaction
BiopsyHypercellular mass with groups of neoplastic chondrocytes and extensive chondroid matrix component; Tumor cells with enlarged hyperchromatic nuclei and occasional binucleation; Some bony fragments are also present; Immunohistochemical positivity for S100 positive and focal positivity for IDH-1
Surgical interventionRadical tumor resection followed by chest wall reconstruction with a locking plate and cement spacer; Pathology suggested grade II chondrosarcoma
Admission courseThe patient was discharged 1 wk after the surgery without complication
Postoperative 1-year follow-up1-yr follow-up: Improved CS, NSS and OSS; No evidence of local recurrence; Further consecutive follow-up needed