Hyperprolactinemia due to pituitary metastasis: A case report

Table 1 Basic preoperative and postoperative endocrinology evaluation

Hormone	Measurement level, preoperative	Measurement level, postoperative	Normal level
TSH	4.990 μIU/mL	8.100 μIU/mL	0.27–4.2n μIU/mL
T4	3.89 pmol/L	4.67 pmol/L	12.0–22.0 pmol/L
T3	4.66 pmol/L	1.81 pmol/L	3.1–6.8 pmol/L
FSH	0.470 mIU/mL	0.530 mIU/mL	1.27–19.26 mIU/mL
LH	< 0.2 mIU/mL	0.030 mIU/mL	1.24 –8.62 mIU/mL
GH	0.207 ng/mL	0.389 ng/mL	0.003–0.971 ng/mL
PRL	703.35 mIU/mL	578.86 mIU/mL	55.97–278.36 mIU/mL
24-h urine output	4.600 L/24 h	3.900 L/24 h	1.5-2.5 L/24 h
Free cortisol (8:00 am)	67.16 nmol/L	141.60 nmol/L	240–619 nmol/L

FSH: Follicle stimulating hormone; LH: Luteinizing hormone; GH: Growth hormone; PRL: Prolactin.

Table 2 Literature review on hyperprolactinemia in patients with pituitary metastasis

Patients	Ref.	Gender	Age in yr	Clinical symptoms	PRL level	Mode of operation	Postoperative symptoms	Primary tumor	Postoperative survival time
1	Yao et al[8]	M	67	Headache, left eyelid prolapse	1022 ng/mL	Endoscopic transsphenoidal surgery	Headache relief	Lung adenocarcinoma	3 mo
2	Thewjitcharoen et al[9]	M	65	Visual impairment, left eyelid prolapse	254 ng/mL	Transsphenoidal subtotal resection	Vision returned to normal	Colorectal cancer	9 mo
3	Stojanović et al[10]	F	67	Visual impairment	1270 mU/L	Transcranial surgery	No improvement	Thyroid carcinoma	2 wk
4	Komninos et al[1]	M	68	Headache, visual impairment	438.6 ng/mL	Transsphenoidal decompression	Headache relief	Liver cancer	3 mo
5	Present case	M	53	Visual impairment, dizziness	703 mIU/mL	Transnasal subtotal sphenotomy	Improvement of vision and dizziness	Lung adenocarcinoma	4 mo