Case Report
Copyright ©The Author(s) 2020.
World J Clin Cases. Mar 6, 2020; 8(5): 946-953
Published online Mar 6, 2020. doi: 10.12998/wjcc.v8.i5.946
Table 1 Trends of the patient's clinical and laboratory data
DaySerum K+ (mmol/L)Serum Na+ (mmol/L)Serum osmolality (mOsm/kg)1.5% NaCl (mL)Urine output (L)
Table 2 Clinical characteristics of central pontine myelinolysis and/or extrapontine myelinolysis associated with vasopressin or its analogs
Ref.Age/sexDrugOriginal diseaseTreatment of hypona-tremiaHypona-tremia improve-ment (mmol/L)LesionsNeuro-logical presentationTherapy for ODSOutcome
Niehaus et al[15], 200116/FAntidiuretic hormoneNocturnal enuresisDiscontinued drug + hypertonic saline10 in 24 h (128 to 138)EPM, CPMConscious disturbancePrednisoloneRecovery
Gutenstein[16], 200739/FDesmopressinHypopituitarySaline38 in 48 h (103 to 141)EPM, CPMDysarthria, hemiplegia, seizuresNADeath
Ranger et al[17], 201013/MDesmopressinCentral DINA60 in 48 h (116 to 176)EPM, CPMComaNADeath
Solà et al[18], 2010NATerlipressinGastrointestinal bleedingDiscontinued drug + hypertonic saline19 in 24 h (109 to 128)ODS,Seizures, comaNARecovery
Zhuang et al[19], 201424/FPituitrinHemoptysisDiscontinued drug + hypertonic saline16 in 24 h (118 to 134)EPMDysarthria, quadriparesis, dystoniaCorticosteroidRecovery
Nabaei et al[20], 201523/FDesmopressinCentral DIDiscontinued drug + hypertonic saline40 in 24 h (126 to166)EPM, CPMQuadriparesis, dysarthria, dysphagiaNASevere brain damage
Hossain et al[21], 201869/MDesmopressinCentral DIDiscontinued drug + hypertonic salineLess than 8 in 24 hCPMNANARecovery