Meta-Analysis
Copyright ©The Author(s) 2020.
World J Clin Cases. Mar 6, 2020; 8(5): 900-911
Published online Mar 6, 2020. doi: 10.12998/wjcc.v8.i5.900
Table 1 Baseline characteristics of the included studies
Ref.NationPublication yearSample size
Age (years, mean ± SD)
BMI (kg/m2, mean ± SD)
NOS scores
TLTGLATGTLTGLATGTLTGLATG
Kim et al[13]Korea2013902358 ± 10.856.8 ± 14.223.2 ± 2.922.2 ± 1.87
Ito et al[20]Japan201411746////6
Kim et al[14]Korea2016272960.8± 9.159.3 ± 13.124 ± 2.923.3 ± 3.27
Kim et al[15]Korea2016302451 ± 12.2554.75 ± 11.2522.2 ± 2.723.6 ± 2.958
Chen et al[16]China201610814559.4± 11.157.3 ± 12.523.5 ± 3.523.1 ± 4.28
Gong et al[19]Korea201742126657.78± 11.255.69 ± 11.96//7
Huang et al[17]China20175145655.5± 12.161.6 ± 11.222.5 ± 13.122.3 ± 13.57
Lu et al[18]China2017252559 ± 8.958.4 ± 7.722.5 ± 2.522.9 ± 3.78
Table 2 Intraoperative and postoperative information in all included studies
OutcomesNumber of studiesSample size
Heterogeneity(P, I2)EffectmodelOverall effect size95%CI of overall effectP value
TLTGLATG
Operation time (min)74487480.29, 18%RWMD = -4.84-11.62-1.950.16
Anastomotic time (min)21351740.009, 85%RWMD = 9.36-1.32-20.040.09
Tumor size (cm)77529680.009, 65%RWMD = -0.43-0.89-0.040.07
Proximal margin (cm)5611489< 0.001, 87%RWMD = -0.56-1.39-0.270.18
Intraoperative blood loss (mL)6358725< 0.001, 76%RWMD = -35.37-61.69--9.060.008
Number of lymph nodes removed67279430.06, 52%RWMD = 3.110.63-5.600.01
Postoperative VAS pain scores
Peak pain score25112890.09, 66%RWMD = 0.17-0.71-1.050.70
POD #1 (8 am)35413130.73, 0%RWMD = -0.01-0.22-0.190.89
POD #3 (8 am)35413130.02, 73%RWMD = -0.17-0.61-0.270.45
POD #5 (8 am)24512900.40, 0%RWMD = -0.19-0.39-0.010.07
Time to first flatus (d)53016780.41, 0%RWMD = 0.07-0.09-0.220.40
Time to first oral intake (d)63317020.16, 37%RWMD = -0.31-0.67-0.060.10
Postoperative hospital stay (d)63317020.18, 34%RWMD = -0.78-1.74-0.190.11
Anastomosis-related complications886910140.29, 18%ROR = 0.730.38-1.400.34
Overall postoperative complications67015120.57, 0%ROR = 1.000.75-1.320.97