Balaban DV, Mihai A, Dima A, Popp A, Jinga M, Jurcut C. Celiac disease and Sjögren’s syndrome: A case report and review of literature. World J Clin Cases 2020; 8(18): 4151-4161 [PMID: 33024773 DOI: 10.12998/wjcc.v8.i18.4151]
Corresponding Author of This Article
Mariana Jinga, MD, PhD, Professor, Internal Medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, Dr. Carol Davila Central Military Emergency University Hospital, No. 37 Dionisie Lupu, Bucharest 020021, Romania. mariana_jinga@yahoo.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
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Table 3 Clinical scenarios needing the search of celiac disease in Sjögren syndrome patients or Sjögren syndrome in celiac disease patients
When to consider CD in SS patients?
When to consider SS in CD patients?
Suggestive gastrointestinal symptoms; Suspected malabsorption; Hypogammaglobulinemia and low levels of total protein; High levels of transaminases without evident cause; Anemia of unknown cause; Herpetiform dermatitis; Autoimmune thyroiditis (frequent in SS patients)[47]1
Dry eyes and dry mouth symptoms; Enlarged parotid glands; Hypergammaglobulinemia and high levels of total protein; Polyneuropathy; Arthritis (arthralgias?); Purpura
Table 4 Future agenda
Describing the prevalence of SS in patients with CD using the new classification criteria for SS
Describing the prevalence of CD in SS patients using newer generation serology tests
Prospective studies in patients with both conditions regarding evolution and prognosis, especially regarding the possible additive risk of lymphoma
Describing the role of gluten free diet regarding SS symptoms in patients associating both diseases
Developing clear recommendations for screening for SS in CD and for CD in SS
Citation: Balaban DV, Mihai A, Dima A, Popp A, Jinga M, Jurcut C. Celiac disease and Sjögren’s syndrome: A case report and review of literature. World J Clin Cases 2020; 8(18): 4151-4161