Case Report
Copyright ©The Author(s) 2019.
World J Clin Cases. Feb 26, 2019; 7(4): 473-481
Published online Feb 26, 2019. doi: 10.12998/wjcc.v7.i4.473
Table 1 Markers used
MarkerCloneSourceAntigen retrievalDilutionsVisualization kit manufacturer
α SMA1A4DAKOMicrowave oven, citrate, pH 61:400DAKO, EnVision
CalponinEP798YLab VisionMicrowave oven, citrate, pH 61:100DAKO, EnVision
H-caldesmonh-CALDLabVisionWater bath, citrate, pH 61:300DAKO, EnVision
CD34L-ENDNOVOCASTRAMicrowave oven, citrate, pH 61:100DAKO, EnVision
p53DO-7NOVOCASTRAMicrowave oven, citrate, pH 61:50DAKO, EnVision
Ki67MIB-1DAKOMicrowave oven, DAKO 1700, pH 61:100DAKO, EnVision
ER6F11NOVOCASTRAMicrowave oven, citrate, pH 61:100DAKO, EnVision
PRPGR 312NOVOCASTRAMicrowave oven, citrate, pH 61:100DAKO, EnVision
EBVCS.1-4DAKOMicrowave oven, DAKO 1700, pH 61:100DAKO, EnVision
Table 2 A summary of primary thyroid LMS as reported in the literature (limited to the English language)
Ref.AgeSexInitial symptomsTumor size in cmILMNIDMTherapyOutcome
[4]74FMass ongoing for 4 mo, pain12++CTDWD, 1 mo
[5]82MMass for 1 mo, dysphonia5.5--Lobectomy + NDDWD 4 mo, RS
[6]54FMass???LobectomyAlive, 15 mo, NED
[7]????+??Alive, 12 mo
[8]54FNo symptoms3.5??LobectomyAlive, 15 mo, NED
[9]72FMass ongoing for 7 mo3--Lobectomy + NDDWD, 51 mo, MD
[3]64FMass7.5?+Uncompleted surgeryDWD, 5 mo, MD
[3]45MMass ongoing for 1 mo9?+Lobectomy, CTAlive, 11 mo, MD
[3]68MMass, dysphonia1.9?+Uncompleted surgeryDWD, 18 mo, MD
[3]83MRapid growing mass, dysphagia5.5?+SurgeryDWD, 3 mo, MD
[10]58FMass5--Total thyroidectomy + NDAlive, 25 mo, NED
[11]6MMass5-+TumorectomyNo follow up after 4 mo, MD
[12]90FBreathing disorder and a mass growing for 1 mo8??Partial tumorectomy + trachelectomy,DWD, 2 mo, pneumonia
[13]66FMass rapidly growing for ? mo8.5-?Thyroidectomy, laryngectomyAlive 3 mo, MD, RS
[14]43MGrowing mass over 2 mo6-+Thyroidectomy + ND, CTDWD 6 mo
[15]83FMass, pain in the arm6.7?-Biopsy, palliative therapyDWD 2 mo, RS
[16]63FMass, weight loss, dysphagia7?+Total thyroidectomyDWD, 5 mo
[17]65FMass, weight loss, cough8--Total thyroidectomy + ND, CTDWD 4 mo
[18]-------
[19]65MLeft arm pain9--Total thyroidectomy, partial esophagetomyAlive after 5 yr of follow up
[20]72FNeck mass with accompanying skin fistulae8.5--Lobectomy with mass excisionDWD, 2 mo
[21]64F---+Total thyroidectomyDWD, 3 mo
[22]56MNeck mass dysphonia, dysphagia3--Total thyroidectomy + NDDWD, 8 mo
[23]39MWeight loss, dysphagia2.5-+Biopsy + RTDWD 3 mo
[23]72FMass, breathing disorder?++Trachelectomy + biopsyDWD, 1.5 mo
[25]65FNeck mass dysphonia8.3-+Total thyroidectomy + lymphadenectomy?
[25]83MNeck mass, dysphonia13--Lobectomy, partial trachelectomy, CTDWD, 5 mo, MD
[26]32FNeck mass5--Lobectomy, RT + CT?
Our Case60FMass, dysphonia, breathing disorder2.5--Total thyroidectomy, RT + CTAlive 17 mo, MD, thrombosis