Efficacy of 1.2 L polyethylene glycol plus ascorbic acid for bowel preparations

Table 1 Clinical characteristics

	1.2 L PEG-ASC (n = 156)	PEG-ELS (n = 156)	Total (n = 312)	P value
Age (mean, range)	62.6 (19-89)	63.5 (24-89)	63.0 (19-89)	0.21
Sex (male, %)	93 (59.6)	84 (53.8)	177 (56.7)	0.30
Constipation, n (%)	39 (25.0)	38 (24.4)	77 (24.7)	0.89
Abdominal operation, n (%)	58 (37.2)	55 (35.3)	113 (36.2)	0.72
Hypertension, n (%)	36 (23.1)	26 (16.7)	62 (19.9)	0.16
Diabetes, n (%)	12 (7.7)	15 (9.6)	27 (8.7)	0.54
Experience of colonoscopy, n (%)	89 (57.0)	87 (55.8)	176 (56.4)	0.81
Indications for colonoscopy, n (%)
Occult blood test-positive	76 (48.7)	70 (44.9)	146 (46.8)	0.50
Surveillance	30 (19.2)	27 (17.3)	57 (18.3)	0.66
Screening	21 (13.5)	22 (14.1)	43 (13.8)	0.87
Blood in stool	10 (6.4)	13 (8.3)	23 (7.4)	0.52
Abdominal pain	5 (3.2)	6 (3.9)	13 (4.2)	0.76
Constipation	4 (2.6)	5 (3.2)	9 (2.9)	0.74
Diarrhea	2 (1.3)	5 (3.2)	7 (2.2)	0.44
Other reason	8 (5.1)	8 (5.1)	16 (5.1)	0.80

PEG-ASC: Polyethylene glycol plus ascorbic acid; PEG-ELS: Polyethylene glycol-based electrolyte solution.

Table 2 Successful cleansing rates according to colonic segment % (n)

	1.2 L PEG-ASC (n = 148)	PEG-ELS (n = 143)	P value
Right	93.9 (139)	94.4 (135)	0.86
Transverse	95.9 (142)	95.1 (136)	0.73
Left	95.9 (142)	92.3 (132)	0.19
Over all	91.9 (136)	90.2 (129)	0.61

BBPS: Boston bowel preparation scale; PEG-ASC: Polyethylene glycol plus ascorbic acid; PEG-ELS: Polyethylene glycol-based electrolyte solution.

Table 3 Successful cleansing rates according to various factors % (n)

	1.2 L PEG-ASC	PEG-ELS	P-value
Age (70 years old and older)	89.8 (44)	89.6 (43)	0.77
Sex (Female)	93.2 (55)	87.7 (57)	0.46
Constipation	81.1 (30)	88.6 (31)	0.58
Diabetes	83.3 (10)	81.3 (13)	0.72
History of abdominal operation	93.1 (54)	92.7 (51)	0.77

PEG-ASC: Polyethylene glycol plus ascorbic acid; PEG-ELS: Polyethylene glycol-based electrolyte solution.

Table 4 The Polyp detection rate, the adenoma detection rate, and the advanced adenoma detection rate % (n)

Variable	1.2 L PEG-ASC (n = 148)	PEG-ELS (n = 143)	P value
PDR	42.6 (63)	47.6 (68)	0.39
ADR	34.5 (51)	39.1 (56)	0.41
AADR1	10.8 (16)	13.2 (19)	0.52

¹Adenoma ≥ 10 mm in diameter, with villous components or high grade dysplasia.

PDR: Polyp detection rate; ADR: Adenoma detection rate; AADR: Advanced adenoma detection rate.

Table 5 Adverse events % (n)

	1.2 L PEG-ASC	PEG-ELS	P value
Nausea	6.1 (9)	12.6 (18)	0.087
Vomiting	0.7 (1)	2.8 (4)	0.34
Abdominal discomfort	9.5 (14)	7.7 (11)	0.59
Abdominal pain	2.7 (4)	3.5 (5)	0.96
Dizziness	0 (0)	2.1 (3)	0.23
Chill	1.4 (2)	2.1 (3)	0.97
No discomfort	81.8 (120)	76.2 (109)	0.31

PEG-ASC: Polyethylene glycol plus ascorbic acid; PEG-ELS: Polyethylene glycol-based electrolyte solution.