Peritoneal cancer after bilateral mastectomy, hysterectomy, and bilateral salpingo-oophorectomy with a poor prognosis: A case report and review of the literature

Table 1 High-throughput sequencing results

Gene	Mutation description	Mutation type	Mutant species	Clinical significance
BRCA1	c.5085dupT (p.Val1696Cysfs*3)	Frameshift mutation	Heterozygous mutation	Pathogenic
BRCA2	No pathogenic mutations detected	/	/	/

Table 2 Reported cases of primary peritoneal carcinoma after preventive surgery stratified by BRCA1/2 mutation

Ref.	Age at PS (yr)	Previous breast cancer	Procedure	Interval between PS and PPC (mo)	Follow-up time (mo)	Status	BRCA1/2 mutation
Rebbeck et al[4]	N/A	NO	SO	46	N/A	N/A	BRCA1
	N/A	NO	SO	103	N/A	N/A	BRCA1
Casey et al[5]	45	NO	Hyst-BSO	45	24	DOD	BRCA1
	38	NO	Hyst-BSO	67	24	DOD	BRCA1
	48	YES	Hyst-BSO	21	11	DOD	BRCA1
	44	YES	Hyst-BSO	13	48	DOD	BRCA1
	31	YES	BSO	292	13	DOD	BRCA1
Zakhour et al[7]	39	NO	BSO	65	27	DOD	BRCA1
	47	NO	BSO	126	24	Alive	BRCA1
	62	YES	BSO	19	24	Alive	BRCA1
Olivier et al[10]	60	NO	SO	27	22	Alive	BRCA1
	53	NO	SO	33	53	DOD	BRCA1
	64	NO	SO	70	20	Alive	BRCA1
Powell et al[11]1	N/A	N/A	BSO	84	12	DOD	BRCA1
	N/A	N/A	BSO	12	72	DOD	BRCA1
	N/A	N/A	BSO	60	60	Alive	BRCA1
Finch et al[12]1	46	NO	Hyst-BSO	36	36	DOD	BRCA2
	44	YES	BSO	12	48	DOD	BRCA1
	38	NO	BSO	60	36	DOD	BRCA1
	51	YES	Hyst-BSO	48	24	Alive	BRCA1
	36	NO	Hyst-BSO	24	24	Alive	BRCA1
	55	YES	BSO	24	24	DOD	BRCA1
	51	NO	BSO	240	12	Alive	BRCA1
Meeuwissen et al[13]	61	N/A	SO	14	12	DOD	BRCA1
Rabban et al[14]	N/A	N/A	BSO	62	24	DOD	BRCA1
	N/A	N/A	BSO	22	45	Alive	BRCA1
Hill et al[15]1	56	N/A	BSO	60	36	Alive	BRCA1
Powell et al[16]1	N/A	N/A	BSO	60	N/A	N/A	BRCA1
	N/A	N/A	BSO	60	N/A	N/A	BRCA1
Rhiem et al[17]	57	NO	BSO	26	12	Alive	BRCA1

¹These articles do not provide a specific number of months, and the data were converted from number of years. PS: Preventive surgery; Hyst-BSO: Hysterectomy and bilateral salpingo-oophorectomy; BSO: Bilateral salpingo-oophorectomy; SO: Bilateral oophorectomy; DOD: Dead of disease; N/A: Not available.