Systematic Review
Copyright ©The Author(s) 2019.
World J Clin Cases. Nov 6, 2019; 7(21): 3505-3516
Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3505
Table 1 The results of general characteristics
ItemNumber of case reports (%, 95%CI)
Year of publication
Before CARE (1984.1-2013.7)150 (81.5, 75.1-86.9)
After CARE (2013.8-2017.12)34 (18.5, 13.1-24.9)
Journal’s IF
IF < 1.826 (14.1, 9.4-20.0)
IF ≥ 1.8158 (85.9, 80.0-90.6)
Different countries
Developing countries14 (7.6, 4.2-12.4)
Developed countries170 (92.4, 87.6-95.8)
Funding sources
With fundings10 (5.4, 2.6-9.8)
No fundings174 (94.6, 90.2-97.4)
Number of authors
One author61 (33.2, 26.4-40.5)
Two to four authors101 (54.9, 47.4-62.2)
More than four authors22 (12.0, 7.6-17.5)
Number of author’s affiliation
One affiliation115 (62.5, 55.1-69.5)
More than one affiliation69 (37.5, 30.5-44.9)
Number of pages
One page1 (0.5, 0.0-3.0)
Two to four pages87 (47.3, 39.9-54.8)
More than four pages96 (52.2, 44.7-59.6)
Table 2 The scores of the CARE guidelines assessments
ScoreYr of publication
Journal’s IF
Different countries
Funding sources
In total
Before 2013, n = 150After 2013, n = 34IF < 1.8, n = 26IF ≥ 1.8, n = 158Developing countries, n = 14Developed countries, n = 170With funding, n = 10No reported, n = 174
Mean± SD13.5 ± 2.414.2 ± 2.113.3 ± 2.313.6 ± 2.414.4 ± 2.513.5 ± 2.314.2 ± 1.713.6 ± 2.415.6 ± 2.3
P valueP = 0.1114P = 0.4977P = 0.1687P = 0.4456
Range [No. (percentage,95%CI)]
≤ 1018 (12.0, 7.3-18.3)1 (2.9, 0.1-15.3)2 (7.7, 0.9-25.1)17 (10.8, 6.4-16.7)1 (7.1, 0.2-33.9)18 (10.6, 6.4-16.2)0 (0.0, 0.0-30.8)19 (10.9, 6.7-16.5)19 (10.3, 6.3-15.7)
10.5-14.580 (53.3, 45.0-61.5)17 (50.0, 32.4-67.6)17 (65.4, 44.3-82.8)80 (50.6, 42.6-58.7)5 (35.7, 12.8-64.9)92 (54.1, 46.3-61.8)6 (60.0, 26.2-87.8)91 (52.3, 44.6-59.9)97 (52.7, 45.2-60.1)
≥ 1552 (34.7, 27.1-42.9)16 (47.1, 29.8-64.9)7 (26.9, 11.6-47.8)61 (38.6, 31.0-46.7)8 (57.1,28.9-82.3)60 (35.3, 28.1-43.0)4 (40.0, 12.2-73.8)64 (36.8, 29.6-44.4)68 (37.0, 30.0-44.4)
Table 3 The results of the CARE guidelines assessments
ItemsYr of publication
Journal’s IF
Different countries
Funding sources
In total
Before 2013, n = 150After 2013, n = 34IF < 1.8, n = 26IF ≥ 1.8, n = 158Developing countries, n = 14Developed countries, n = 170With funding, n = 10No reported, n = 174
168 (45.3, 37.2-53.7)9 (26.5, 12.9-44.4)11 (42.3, 23.4-63.1)66 (41.8, 34.0-49.9)3 (21.4, 4.7-50.8)74 (43.5, 36.0-51.3)7 (70.0, 34.8-93.3)70 (40.2, 32.9-47.9)77 (41.8, 34.6-49.3)
270 (46.7, 38.5-55.0)23 (67.6, 49.5-82.6)15 (57.7, 36.9-76.6)78 (49.4, 41.3-57.4)9 (64.3, 35.1-87.2)84 (49.4, 41.7-57.2)2 (20.0, 2.5-55.6)91 (52.3, 44.6-59.9)93 (50.5, 43.1-58.0)
3a86 (57.3, 49.0-65.4)19 (55.9, 37.9-72.8)14 (53.8, 33.4-73.4)91 (57.6, 49.5-65.4)13 (92.9, 66.1-99.8)92 (54.1, 46.3-61.8)7 (70.0, 34.8-93.3)98 (56.3, 48.6-63.8)105 (57.1, 49.6-64.3)
3b85 (56.7, 48.3-64.7)19 (55.9, 37.9-72.8)5 (19.2, 6.6-39.4)99 (62.7, 54.6-70.2)9 (64.3, 35.1-87.2)95 (55.9, 48.1-63.5)8 (80.0, 44.4-97.5)96 (55.2, 47.5-62.7)104 (56.5, 49.0-63.8)
3c89 (59.3, 51.0-67.3)20 (58.8, 40.7-75.4)10 (38.5, 20.2-59.4)99 (62.7, 54.6-70.2)8 (57.1, 28.9-82.3)101 (59.4, 51.6-66.9)8 (80.0, 44.4-97.5)101 (58.0, 50.3-65.5)109 (59.2, 51.8-66.4)
480 (53.3, 45.0-61.5)26 (76.5, 58.8-89.3)22 (84.6, 65.1-95.6)84 (53.2, 45.1-61.1)10 (71.4, 41.9-91.6)96 (56.5, 48.7-64.0)6 (60.0,26.2-87.8)100 (57.5, 49.8-64.9)106 (57.6, 50.1-64.8)
5a137 (91.3, 85.6-95.3)33 (97.1, 84.7-99.9)25 (96.2, 80.4-99.9)142 (89.9, 84.1-94.1)14 (100.0, 76.8-100.0)153 (90.0, 84.5-94.1)9 (90.0, 55.5-99.7)158 (90.8, 85.5-94.7)167 (90.8, 85.6-94.5)
5b100 (66.7, 58.5-74.1)26 (76.5, 58.8-89.3)20 (76.9, 56.4-91.0)106 (67.1, 59.2-74.3)9 (64.3, 35.1-87.2)117 (68.8, 61.3-75.7)7 (70.0, 34.8-93.3)119 (68.4, 60.9-75.2)126 (68.5, 61.2-75.1)
5c10 (6.7, 3.2-11.9)3 (8.8, 1.9-23.7)3 (11.5, 2.4-30.2)10 (6.3, 3.1-11.3)1 (7.1, 0.2-33.9)12 (7.1, 3.7-12.0)1 (10.0, 0.3-44.5)12 (6.9, 3.6-11.7)13 (7.1, 3.8-11.8)
6140 (93.3, 88.1-96.8)31 (91.2, 76.3-98.1)24 (92.3, 74.9-99.1)147 (93.0, 87.9-96.5)12 (85.7, 57.2-98.2)159 (93.5, 88.7-96.7)9 (90.0, 55.5-99.7)162 (93.1, 88.3-96.4)171 (92.9, 88.2-96.2)
7105 (70.0, 62.0-77.2)20 (58.8, 40.7-75.4)13 (50.0, 29.9-70.1)112 (70.9, 63.1-77.8)9 (64.3, 35.1-87.2)116 (68.2, 60.7-75.2)7 (70.0, 34.8-93.3)118 (67.8, 60.3, 74.7)125 (67.9, 60.7-74.6)
8a127 (84.7, 779-90.0)31 (91.2, 76.3-98.1)22 (84.6, 65.1-95.6)136 (86.1, 79.7-91.1)13 (92.9, 66.1-99.8)145 (85.3, 79.1-90.3)8 (80.0, 44.4-97.5)150 (86.2, 80.2-91.0)158 (85.9, 80.0-90.6)
8b27 (18.0, 12.2-25.1)8 (23.5, 10.7-41.2)5 (19.2, 6.6-39.4)30 (19.0, 13.2-26.0)5 (35.7, 12.8-64.9)30 (17.6, 12.2-24.2)1 (10.0, 0.3-44.5)34 (19.5, 13.9-26.2)35 (19.0, 13.6-25.4)
8c148 (98.7, 95.3-99.8)34 (100.0, 89.7-100.0)26 (100.0, 86.8-100.0)156 (98.1, 95.5-99.8)14 (100.0, 76.8-100.0)168 (98.8, 95.8-99.9)10 (100.0,69.2-100.0)172 (98.9, 95.9-99.9)182 (98.9, 96.1-99.9)
8d1 (0.7, 0.0-3.7)2 (5.9, 0.7-19.7)1 (3.8, 0.1-19.6)2 (1.3, 0.2-4.5)0 (0.0, 0.0-23.2)3 (1.8, 0.4-5.1)0 (0.0,0.0-30.8)3 (1.7, 0.4-5.0)3 (1.6, 0.3-4.7)
9147 (98.0, 94.3-99.6)32 (94.1, 80.3-99.3)24 (92.3, 74.5-99.1)155 (98.1, 94.6-996)13 (92.9, 66.1-99.8)166 (97.6, 94.1-99.4)9 (90.0, 55.5-99.7)170 (97.7, 94.2-99.4)179 (97.3, 93.8-99.1)
103 (2.0, 0.4-5.7)2 (5.9, 0.7-19.7)2 (7.7, 0.9-25.1)3 (1.9, 0.4-5.4)0 (0.0, 0.0-23.2)5 (2.9, 1.0-6.7)1 (10.0, 0.3-44.5)4 (2.3, 0.6-5.8)12 (6.5, 3.4-11.1)
11a104 (69.3, 61.3-76.6)23 (67.6, 49.5-82.6)19 (73.1, 52.2-88.4)108 (68.4, 60.5-75.5)11 (78.6, 49.2-95.3)116 (68.2, 60.7-75.2)6 (60.0,26.2-87.8)121 (69.5, 62.1-76.3)127 (69.0, 61.8-75.6)
11b88 (58.7, 50.3-66.6)30 (88.2, 72.5-96.7)18 (69.2, 48.2-85.7)100 (63.3, 55.3-70.8)9 (64.3, 35.1-87.2)109 (64.1, 56.4-71.3)9 (90.0, 55.5-99.7)109 (62.6, 55.0-69.8)118 (64.1, 56.7-71.1)
11c113 (75.3, 67.6-82.0)17 (50.0, 32.4-67.6)15 (57.7, 36.9-76.6)115 (72.8, 65.1-79.6)11 (78.6, 49.2-95.3)119 (70.0, 62.5-76.8)7 (70.0, 34.8-93.3)123 (70.7, 63.3-77.3)130 (70.7, 63.5-77.1)
11d138 (92.0, 86.4-95.8)33 (97.1, 84.7-99.9)26 (100.0, 86.8-100.0)145 (91.8, 86.3-95.5)13 (92.9, 66.1-99.8)158 (92.9, 88.0-96.3)10 (100.0,69.2-100.0)161 (92.5, 87.6-96.0)171 (92.9, 88.2-96.2)